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酒石酸泰乐菌素

酒石酸泰乐菌素用途

对支原体有特效，用作抗支原体病的首选药物

酒石酸泰乐菌素名称

[ CAS 号 ]:
1405-54-5

[ 中文名 ]:
泰乐霉素

[ 英文名 ]:
1405-54-5

[中文别名 ]:

[英文别名 ]:

TYLOSINTARTRATE,BP
pharmasin
TYLOSINE TARTRATE
Tylosin,(2R,3R)-2,3-dihydroxybutanedioate (salt)
TYLOSINTARTRATEPOWDER/GRANULAR
Tylosin Tartrate,For Veterinary Use,BP
Tylosin (2R,3R)-2
Tylosin Tartrate (100 mg)
Tylosin Tartrate
TYLOSIN TARTRATE SALT

酒石酸泰乐菌素物理化学性质

[ 密度 ]:
1.24 g/cm3

[ 沸点 ]:
1116.3ºC at 760 mmHg

[ 分子式 ]:
C₄₉H₈₁NO₂₃

[ 分子量 ]:
1052.160

[ 闪点 ]:
628.9ºC

[ 精确质量 ]:
1051.519897

[ PSA ]:
353.73000

[ 外观性状 ]:
白色至淡黄色粉末

[ 蒸汽压 ]:
0mmHg at 25°C

[ 储存条件 ]:
2-8°C

酒石酸泰乐菌素MSDS

详细MSDS(安全技术说明书)

酒石酸泰乐菌素毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YP0875000

CHEMICAL NAME :: Tylosin, tartrate

CAS REGISTRY NUMBER :: 1405-54-5

LAST UPDATED :: 199806

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C45-H77-N-O17.C4-H6-O6

MOLECULAR WEIGHT :: 1054.33

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >6200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AAGAAW Antimicrobial Agents Annual. (New York, NY) 1960. For publisher information, see AMACCQ. Volume(issue)/page/year: -,595,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 695 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 4,1,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >6200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AAGAAW Antimicrobial Agents Annual. (New York, NY) 1960. For publisher information, see AMACCQ. Volume(issue)/page/year: -,595,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1354 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 4,1,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 589 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 4,1,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AAGAAW Antimicrobial Agents Annual. (New York, NY) 1960. For publisher information, see AMACCQ. Volume(issue)/page/year: -,595,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 5400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AAGAAW Antimicrobial Agents Annual. (New York, NY) 1960. For publisher information, see AMACCQ. Volume(issue)/page/year: -,595,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 620 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - irritability

REFERENCE :: VMDNAV Veterinarno-Meditsinski Nauki. Veterinary Science. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1964- Volume(issue)/page/year: 15,52,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 48 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - irritability

REFERENCE :: VMDNAV Veterinarno-Meditsinski Nauki. Veterinary Science. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1964- Volume(issue)/page/year: 15,52,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 432 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AAGAAW Antimicrobial Agents Annual. (New York, NY) 1960. For publisher information, see AMACCQ. Volume(issue)/page/year: -,595,1960 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 5400 mg/kg/6W-I

TOXIC EFFECTS :: Blood - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: VMDNAV Veterinarno-Meditsinski Nauki. Veterinary Science. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1964- Volume(issue)/page/year: 15,52,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2751 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 99 (estimated)

酒石酸泰乐菌素安全信息

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R42/43

[ 安全声明 (欧洲) ]:
S22-S36/37