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依酚氯铵

依酚氯铵用途

Edrophonium chloride是乙酰胆碱酯酶可逆性抑制剂。

依酚氯铵名称

[ CAS 号 ]:
116-38-1

[ 中文名 ]:
依酚氯铵

[ 英文名 ]:
Edrophonium chloride

[中文别名 ]:

[英文别名 ]:

edrophonium chloride
MFCD00055064
EINECS 204-138-4
Ethyl(m-hydroxyphenyl)dimethylammonium chloride
Tensilon
N-Ethyl-3-hydroxy-N,N-dimethylanilinium chloride
ethyl-(3-hydroxyphenyl)-dimethylazanium,chloride
Edrophonium (chloride)

依酚氯铵生物活性

[ 描述 ]:

Edrophonium chloride是乙酰胆碱酯酶可逆性抑制剂。

[ 相关类别 ]:

信号通路 >> 神经信号通路 >> 疼痛

研究领域 >> 神经疾病

[相关活性小分子]

依酚氯铵物理化学性质

[ 密度 ]:
1.395 g/mL at 25 °C(lit.)

[ 沸点 ]:
130 °C20 mm Hg(lit.)

[ 熔点 ]:
162-163°C

[ 分子式 ]:
C₁₀H₁₆ClNO

[ 分子量 ]:
201.693

[ 闪点 ]:
>230 °F

[ 精确质量 ]:
201.092041

[ PSA ]:
20.23000

[ 外观性状 ]:
白色粉末

[ 折射率 ]:
n20/D 1.486(lit.)

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
reacts

依酚氯铵MSDS

详细MSDS(安全技术说明书)

依酚氯铵毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BQ5870000

CHEMICAL NAME :: Ammonium, ethyl(m-hydroxyphenyl)dimethyl-, chloride

CAS REGISTRY NUMBER :: 116-38-1

LAST UPDATED :: 199504

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H16-N-O.Cl

MOLECULAR WEIGHT :: 201.72

WISWESSER LINE NOTATION :: QR CK2&1&1 &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 10,327,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 52 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - muscle weakness

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 123,121,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 115,185,1955 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5548 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 8250 (estimated) No. of Female Employees: 7491 (estimated)

依酚氯铵安全信息

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
BQ5870000

[ 海关编码 ]:
2923900090

依酚氯铵合成路线

详细合成路线

依酚氯铵上下游产品

依酚氯铵上游产品

依酚氯铵下游产品

依酚氯铵海关

[ 海关编码 ]: 2923900090

[ 中文概述 ]:
2923900090 其他季铵盐及季铵碱。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%