(S)-N-甲基-3-(4-三氟甲基苯氧基)-3-苯基丙基胺盐酸盐

用途

Fluoxetine hcl (hydrochloride) is a selective serotonin reuptake inhibitor and functions as an antidepressant. This drug works at presynaptic terminals where it prevents the reuptake of serotonin, resulting in the accumulation of serotonin in extracellular fluid at synapses.

名称

[ CAS 号 ]:
114247-06-2

[ 中文名 ]:
(S)-N-甲基-3-(4-三氟甲基苯氧基)-3-苯基丙基胺盐酸盐

[ 英文名 ]:
S-(+)-FLUOXETINE HYDROCHLORIDE

[英文别名 ]:

物理化学性质

[ 沸点 ]:
395.1ºC at 760 mmHg

[ 分子式 ]:
C17H19ClF3NO

[ 分子量 ]:
345.78700

[ 闪点 ]:
192.8ºC

[ 精确质量 ]:
345.11100

[ PSA ]:
21.26000

[ LogP ]:
5.62790

[ 外观性状 ]:
固体

[ 蒸汽压 ]:
1.88E-06mmHg at 25°C

[ 储存条件 ]:
室温

MSDS

安全信息

[ 符号 ]:

GHS07, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H410

[ 警示性声明 ]:
P301 + P312 + P330

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;N: Dangerous for the environment;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S36/37

[ 危险品运输编码 ]:
UN 3077 9/PG 3

文献

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

Case history: the discovery of fluoxetine hydrochloride (Prozac).

Nat. Rev. Drug Discov. 4(9) , 764-74, (2005)

In the early 1970s, evidence of the role of serotonin (5-hydroxytryptamine or 5-HT) in depression began to emerge and the hypothesis that enhancing 5-HT neurotransmission would be a viable mechanism t...


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热门化合物

CAS号[114247-06-2]化源网提供[(S)-N-甲基-3-(4-三氟甲基苯氧基)-3-苯基丙基胺盐酸盐]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版:(S)-N-甲基-3-(4-三氟甲基苯氧基)-3-苯基丙基胺盐酸盐

标题:114247-06-2_CAS号:114247-06-2_(S)-N-甲基-3-(4-三氟甲基苯氧基)-3-苯基丙基胺盐酸盐 - 化源网 地址:https://www.chemsrc.com/amp/cas/114247-06-2_1104202.html