乙二胺四乙酸四钠盐二水合物

乙二胺四乙酸四钠盐二水合物用途

乙二胺四乙酸(EDTA)钠水合物是一种金属螯合剂(与包括钙在内的金属二价和三价阳离子结合),具有抗凝和抗高钙血症的活性。乙二胺四乙酸钠水合物减少了金属离子催化的蛋白质氧化损伤,并允许在蛋白质纯化过程中维持还原环境。乙二胺四乙酸钠水合物也可以减少二硫键的形成[1][2][3]。

乙二胺四乙酸四钠盐二水合物名称

[ CAS 号 ]:
10378-23-1

[ 中文名 ]:
乙二胺四乙酸四钠盐二水合物

[ 英文名 ]:
Ethylenediaminetetraacetic acid sodium hydrate

[中文别名 ]:

[英文别名 ]:

Ethylenediaminetetraacetic acid tetrasodium salt
EDTA 4Na Dihydrate
Tetrasodium ethylenediaminetetraacetate dihydrate
EDTA-4Na.2H2O
EDTA tetrasodium salt
EINECS 208-924-8
MFCD00007499

乙二胺四乙酸四钠盐二水合物生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 心血管疾病

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[参考文献]

[1]. Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9.

[2]. Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 2007;45(5):565-76.

[3]. Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb;10(1):58-62.

乙二胺四乙酸四钠盐二水合物物理化学性质

[ 沸点 ]:
614.2ºC at 760mmHg

[ 熔点 ]:
>300ºC

[ 分子式 ]:
C₁₀H₁₆N₂Na₄O₁₀

[ 分子量 ]:
416.201

[ 闪点 ]:
325.2ºC

[ 精确质量 ]:
416.039581

[ PSA ]:
185.46000

[ 外观性状 ]:
白色晶体或粉末

[ 储存条件 ]:
Store at RT.

[ 水溶解性 ]:
H2O: clear, colorless

乙二胺四乙酸四钠盐二水合物MSDS

详细MSDS(安全技术说明书)

乙二胺四乙酸四钠盐二水合物安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H318

[ 警示性声明 ]:
P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
DB6145180

[ 海关编码 ]:
29224995

乙二胺四乙酸四钠盐二水合物文献

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Inhibition of in vitro fertilizing capacity of cryopreserved mouse sperm by factors released by damaged sperm, and stimulation by glutathione.

PLoS Biol. 5 , e9387, (2010)

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Bi-allelic gene targeting in mouse embryonic stem cells.

Methods 53 , 331-8, (2011)

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