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5-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-氨基嘌呤-9-基)-4-羟基-3-膦酰氧基四氢呋喃-2-基]甲氧基-羟基磷酰]氧基-羟基磷酰]氧基-2-羟基-3,3-二甲基丁酰基]氨基]丙酰氨基]乙硫基]-5-氧代戊酸

用途

戊二醛辅酶A锂是戊二醛辅酶A的衍生物。谷氨酸辅酶A是一种重要的内源性代谢产物。戊二醛辅酶A锂可用于HMG-CoA或戊二醛CoA相关实验。

名称

[ CAS 号 ]:
103192-48-9

[ 中文名 ]:
谷氨酰辅酶A锂盐

[ 英文名 ]:
Glutaryl coenzyme A lithium

[英文别名 ]:

生物活性

[ 描述 ]:

戊二醛辅酶A锂是戊二醛辅酶A的衍生物。谷氨酸辅酶A是一种重要的内源性代谢产物。戊二醛辅酶A锂可用于HMG-CoA或戊二醛CoA相关实验。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

物理化学性质

[ 密度 ]:
1.88g/cm3

[ 分子式 ]:
C₂₆H₄₁LiN₇O₁₉P₃S

[ 分子量 ]:
887.56700

[ 精确质量 ]:
887.15500

[ PSA ]:
458.49000

[ 外观性状 ]:
固体

[ 折射率 ]:
1.71

[ 储存条件 ]:
20°C

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
22-26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Cerebral haemodynamics in patients with glutaryl-coenzyme A dehydrogenase deficiency.

Brain 133 , 76-92, (2010)

In glutaric aciduria type 1, glutaryl-coenzyme A and its derivatives are produced from intracerebral lysine and entrapped at high concentrations within the brain, where they interfere with energy meta...

Conversion of a decarboxylating to a non-decarboxylating glutaryl-coenzyme A dehydrogenase by site-directed mutagenesis.

FEBS Lett. 585 , 1317-1321, (2011)

Glutaryl-coenzyme A (CoA) dehydrogenases (GDHs) are acyl-CoA dehydrogenases, which usually dehydrogenate and decarboxylate the substrate to crotonyl-CoA. In some anaerobic bacteria, non-decarboxylatin...

Structural basis for promoting and preventing decarboxylation in glutaryl-coenzyme a dehydrogenases.

Biochemistry 49 , 5350-5357, (2010)

Glutaryl-coenzyme A dehydrogenases (GDHs) involved in amino acid degradation were thought to catalyze both the dehydrogenation and decarboxylation of glutaryl-coenzyme A to crotonyl-coenzyme A and CO(...

更多文献