Tween 60

Modify Date: 2024-01-02 10:35:00

Tween 60 Structure
Tween 60 structure
Common Name Tween 60
CAS Number 9005-67-8 Molecular Weight N/A
Density 1.081 Boiling Point 583.8±50.0 °C at 760 mmHg
Molecular Formula C24H46O6.(C2H4O)n Melting Point N/A
MSDS Chinese USA Flash Point 190.4±23.6 °C

 Use of Tween 60


Polyoxyethylene Sorbitan Monostearate is an ester of the saturated fatty acid stearic acid (C18:0). Polyoxyethylene Sorbitan Monostearate can be used as an excipient, such as surfactant, emulsifier, solubilizer, wetting agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

 Names

Name Tween 60
Synonym More Synonyms

 Tween 60 Biological Activity

Description Polyoxyethylene Sorbitan Monostearate is an ester of the saturated fatty acid stearic acid (C18:0). Polyoxyethylene Sorbitan Monostearate can be used as an excipient, such as surfactant, emulsifier, solubilizer, wetting agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog
References

[1]. Lind ML, et al. Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80. Eur J Pharm Sci. 2008 Oct 2;35(3):211-8.  

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.  

 Chemical & Physical Properties

Density 1.081
Boiling Point 583.8±50.0 °C at 760 mmHg
Molecular Formula C24H46O6.(C2H4O)n
Flash Point 190.4±23.6 °C
PSA 133.14000
LogP 8.09
Vapour Pressure 0.0±3.7 mmHg at 25°C
Index of Refraction 1.499
Storage condition Store at RT.
Water Solubility 100 g/L

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
Safety Phrases 24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS WG2934000
HS Code 34021300

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 Synonyms

D-Glucitol, 1,4-anhydro-2,3-bis-O-(2-hydroxyethyl)-6-O-(1-oxododecyl)-
MFCD01780110
1,4-Anhydro-6-O-dodecanoyl-2,3-bis-O-(2-hydroxyethyl)-D-glucitol
Polyoxyethylene sorbitan monostearate
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]thymidine
Polyethylene glycol sorbitan monostearate
polysorbate 60
Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-
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