1-naphthylamine-5-sulfonic acid

Modify Date: 2024-01-08 17:10:51

1-naphthylamine-5-sulfonic acid Structure
1-naphthylamine-5-sulfonic acid structure
Common Name 1-naphthylamine-5-sulfonic acid
CAS Number 84-89-9 Molecular Weight 223.248
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H9NO3S Melting Point >300°C
MSDS Chinese USA Flash Point N/A
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

Name 5-Aminonaphthalene-1-sulfonic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Melting Point >300°C
Molecular Formula C10H9NO3S
Molecular Weight 223.248
Exact Mass 223.030319
PSA 88.77000
LogP 0.42
Index of Refraction 1.713

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QK1270500
CHEMICAL NAME :
1-Naphthalenesulfonic acid, 5-amino-
CAS REGISTRY NUMBER :
84-89-9
BEILSTEIN REFERENCE NO. :
2214149
LAST UPDATED :
199709
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H9-N-O3-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - muscle weakness
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2880 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal)
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - muscle weakness
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2990 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal)
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
30 gm/kg/30D-I
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Liver - liver function tests impaired Blood - pigmented or nucleated red blood cells
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H312-H314-H332
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C:Corrosive;
Risk Phrases R20/21/22;R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 2585 8/PG 3
WGK Germany 3
RTECS QK1270500
Packaging Group III
Hazard Class 8
HS Code 2921450090

 Synthetic Route

 Customs

HS Code 2921450090
Summary 2921450090 1-naphthylamine (α-naphthylamine), 2-naphthylamine (β-naphthylamine) and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles13

More Articles
Identification of a novel ligand binding motif in the transthyretin channel.

Bioorg. Med. Chem. 18 , 100-10, (2010)

The design of therapeutic compounds targeting transthyretin (TTR) is challenging due to the low specificity of interaction in the hormone binding site. Such feature is highlighted by the interactions ...

[An interesting peroxidase staining.--utilization of blended substrate of mixed 2, 7-FDA and Laurent's acid-- (author's transl)].

Rinsho Byori. 29(6) , 613-6, (1981)

Evidence for a ppGpp-binding site on Escherichia coli RNA polymerase: proximity relationship with the rifampicin-binding domain.

Mol. Microbiol. 15(2) , 255-65, (1995)

On amino acid starvation, Escherichia coli cells exhibit an adaptive facility termed the stringent response. This is characterized by the production of high levels of a regulatory nucleotide, ppGpp, a...

 Synonyms

1-naphthylamine-5-sulfonic acid
5-Amino-1-naphthalenesulfonic acid
5-Aminonaphthalene-1-sulfonic acid
MFCD00014315
1-Naphthalenesulfonic acid, 5-amino-
EINECS 201-571-0