Saccharin sodium hydrate

Modify Date: 2024-01-02 17:20:25

Saccharin sodium hydrate structure	Common Name	Saccharin sodium hydrate
	CAS Number	82385-42-0	Molecular Weight	241.19700
	Density	N/A	Boiling Point	438.9ºC at 760 mmHg
	Molecular Formula	C₇H₈NNaO₅S	Melting Point	>300°C
	MSDS	USA	Flash Point	219.3ºC

Use of Saccharin sodium hydrate

Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties[1].

Name	Saccharin, sodium salt hydrate
Synonym	More Synonyms

Description	Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	In vitro, saccharin sodium hydrate (0.5, 2.5, 5 mM) inhibits bacterial growth in a species-dependent manner[1].
In Vivo	In vivo, saccharin sodium hydrate (oral; 5 mg/kg; twice a day) intake reduces fecal bacterial load and alters microbiome composition, while the intestinal barrier is not obviously affected in male C57BL/6JRj wild type (wt) mice[1].
References	[1]. Sünderhauf A, et al. Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice. Nutrients. 2020 Apr 17;12(4). pii: E1122.

Boiling Point	438.9ºC at 760 mmHg
Melting Point	>300°C
Molecular Formula	C₇H₈NNaO₅S
Molecular Weight	241.19700
Flash Point	219.3ºC
Exact Mass	241.00200
PSA	78.05000
LogP	1.18550
Water Solubility	H2O: 1 M at 20 °C, clear, colorless

Saccharin sodium hydrate MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	DE4550000

Fructose- and glucose-conditioned preferences in FVB mice: strain differences in post-oral sugar appetition.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(12) , R1448-57, (2014)

Recent studies indicate that, unlike glucose, fructose has little or no post-oral preference conditioning actions in C57BL/6J (B6) mice. The present study determined whether this is also the case for ...

Common-ion effects on the deliquescence lowering of crystalline ingredient blends.

Food Chem. 195 , 2-10, (2015)

Deliquescence points (RH0, RH0mix) of ionic crystalline food ingredients and blends thereof were determined using water activity and moisture sorption techniques. Measured RH0mix values of ingredient ...

Role of olfaction in the conditioned sucrose preference of sweet-ageusic T1R3 knockout mice.

Chem. Senses 34 , 685-94, (2009)

Prior work has shown that sweet taste-deficient T1R3 knockout (KO) mice developed significant sucrose preferences when given long-term sugar versus water tests. The current study investigated the role...

MFCD00151213

EINECS 204-886-1

saccharin sodium salt dihydrate