H-Pro-Gly-Pro-OH
Modify Date: 2024-01-05 12:22:18
H-Pro-Gly-Pro-OH structure
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Common Name | H-Pro-Gly-Pro-OH | ||
|---|---|---|---|---|
| CAS Number | 7561-51-5 | Molecular Weight | 269.29700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H19N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of H-Pro-Gly-Pro-OHH-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia[1][2]. |
| Name | (2S)-1-[2-[[(2S)-pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
| Description | H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia[1][2]. |
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| Related Catalog | |
| In Vivo | H-Pro-Gly-Pro-OH (37.5 µg/kg; i.p.) 在大鼠脑缺血后激活神经营养蛋白及其受体基因的转录[2]。 Animal Model: 270-320 g, male Wistar rats (focal cerebral ischemia)[2] Dosage: 37.5 µg/kg Administration: I.p.; 15, 1 h, 4, 8, 24, 28, 32, 48, 52, and 56 h Result: Enhanced the transcription of Bdnf and TrkC 3 h after pMCAO and Ngf, TrkB, TrkC, and TrkA 24 h after pMCAO. |
| References |
| Molecular Formula | C12H19N3O4 |
|---|---|
| Molecular Weight | 269.29700 |
| Exact Mass | 269.13800 |
| PSA | 102.23000 |
| LogP | 0.03720 |
| L-Proline,L-prolylglycyl |