Loxoprofen structure
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Common Name | Loxoprofen | ||
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CAS Number | 68767-14-6 | Molecular Weight | 246.302 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 417.9±20.0 °C at 760 mmHg | |
Molecular Formula | C15H18O3 | Melting Point | 108.5 - 111ºC | |
MSDS | Chinese USA | Flash Point | 220.7±18.3 °C |
Use of LoxoprofenLoxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. |
Name | loxoprofen |
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Synonym | More Synonyms |
Description | Loxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. |
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Related Catalog | |
Target |
COX-1:6.5 μM (IC50, in human whole blood) COX-2:13.5 μM (IC50, in human whole blood) |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 417.9±20.0 °C at 760 mmHg |
Melting Point | 108.5 - 111ºC |
Molecular Formula | C15H18O3 |
Molecular Weight | 246.302 |
Flash Point | 220.7±18.3 °C |
Exact Mass | 246.125595 |
PSA | 54.37000 |
LogP | 1.87 |
Vapour Pressure | 0.0±1.0 mmHg at 25°C |
Index of Refraction | 1.568 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2918300090 |
~% Loxoprofen CAS#:68767-14-6 |
Literature: US4161538 A1, ; |
~% Loxoprofen CAS#:68767-14-6 |
Literature: Synthetic Communications, , vol. 14, # 14 p. 1365 - 1372 |
~% Loxoprofen CAS#:68767-14-6 |
Literature: Synthetic Communications, , vol. 14, # 14 p. 1365 - 1372 |
~84% Loxoprofen CAS#:68767-14-6 |
Literature: Hurusawa, Shinya; Nakamura, Shuji; Yagi, Sayoko; Kurihara, Takushi; Hamada, Yasumasa; Shioiri, Takayuki Synthetic Communications, 1984 , vol. 14, # 14 p. 1365 - 1372 |
~% Loxoprofen CAS#:68767-14-6 |
Literature: Journal of Medicinal Chemistry, , vol. 27, # 2 p. 212 - 216 |
HS Code | 2918300090 |
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Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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IOXOPROFEN |
MFCD00864331 |
KOLOXO |
Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]- |
2-{4-[(2-Oxocyclopentyl)methyl]phenyl}propanoic acid |
Loxoprofen |