1,3-DINITROGLYCERIN

Modify Date: 2024-01-07 09:25:27

1,3-DINITROGLYCERIN Structure
1,3-DINITROGLYCERIN structure
Common Name 1,3-DINITROGLYCERIN
CAS Number 623-87-0 Molecular Weight 182.08900
Density 1.594 g/cm3 Boiling Point 170.2ºC at 760 mmHg
Molecular Formula C3H6N2O7 Melting Point 26°C
MSDS N/A Flash Point 56.8ºC
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Names

Name 1,3-dinitroglycerol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.594 g/cm3
Boiling Point 170.2ºC at 760 mmHg
Melting Point 26°C
Molecular Formula C3H6N2O7
Molecular Weight 182.08900
Flash Point 56.8ºC
Exact Mass 182.01800
PSA 130.33000
Index of Refraction 1.489
Storage condition ?20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MA9487500
CHEMICAL NAME :
Glycerol, 1,3-dinitrate
CAS REGISTRY NUMBER :
623-87-0
BEILSTEIN REFERENCE NO. :
1784163
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C3-H6-N2-O7

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1065 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD-B011-150
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
676 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD-B011-150

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H302 + H312 + H332-H319
Precautionary Statements P210-P280-P305 + P351 + P338
Hazard Codes F,Xn
Risk Phrases 11-20/21/22-36
Safety Phrases 16-36/37
RIDADR 0473
Packaging Group II
Hazard Class 1.1A
HS Code 2920909090

 Synthetic Route

 Customs

HS Code 2920909090
Summary 2920909090 esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and their salts; their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles25

More Articles
Biotransformation of glyceryl trinitrate by rat brain homogenate.

Can. J. Physiol. Pharmacol. 70(6) , 935-7, (1992)

Incubation of glyceryl trinitrate (GTN) with 5% (w/v) rat brain homogenate (RBH) resulted in biotransformation of the organic nitrate vasodilator drug to a mixture of glyceryl-1,2-dinitrate (1,2-GDN) ...

Effect of temperature on glyceryl trinitrate induced relaxation of rabbit aorta.

Can. J. Physiol. Pharmacol. 71(8) , 629-32, (1993)

It has previously been shown that the vasodilatory response to glyceryl trinitrate (GTN) was decreased during hypothermic cardiopulmonary bypass. The purpose of these experiments was to determine the ...

Nitroglycerin dinitrate metabolites do not affect the pharmacokinetics and pharmacodynamics of nitroglycerin in the dog: a preliminary report.

J. Pharmacokinet. Biopharm. 21(2) , 163-73, (1993)

Studies were carried out in conscious dogs to determine the effects of 1,2-glyceryl dinitrate (1,2-GDN) and 1,3-glyceryl dinitrate (1,3-GDN) on nitroglycerin (GTN) pharmacokinetics and pharmacodynamic...

 Synonyms

1,3-di-O-nitroglycerol
(2-hydroxy-3-nitrooxypropyl) nitrate
1,3-Dinitroglycerin
1,3-Dng
glycerine 1,3-dinitrate
1,3-Dinitroglycerol
1,2,3-propanetriol 1,3-dinitrate
1,3-Glyceryl dinitrate
Glycerol-1,3-dinitrate
Glyceryl-1,3-dinitrate
1,3-dinitroxy-2-hydoxypropane