[D-Trp6]-LH-RH
![[D-Trp6]-LH-RH Structure](https://www.chemsrc.com/caspic/100/57773-63-4.png)
[D-Trp6]-LH-RH structure
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Common Name | [D-Trp6]-LH-RH | ||
|---|---|---|---|---|
| CAS Number | 57773-63-4 | Molecular Weight | 1311.449 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C64H82N18O13 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS08 |
Signal Word | Danger | |
Use of [D-Trp6]-LH-RHTriptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferationIn vivo: (1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins. |
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Effect of [D-Trp6]-LH-RH |
| Name | triptorelin |
|---|---|
| Synonym | More Synonyms |
| Description | Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferationIn vivo: (1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C64H82N18O13 |
| Molecular Weight | 1311.449 |
| Exact Mass | 1310.630859 |
| PSA | 487.92000 |
| LogP | -0.41 |
| Index of Refraction | 1.723 |
| Storage condition | −20°C |
| Symbol |
GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H360 |
| Precautionary Statements | P201-P308 + P313 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T: Toxic; |
| Risk Phrases | R60 |
| Safety Phrases | 53-22-36/37/39-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Changes in the size of rectovaginal endometriotic nodules infiltrating the rectum during hormonal therapies.
Arch. Gynecol. Obstet. 287(3) , 447-53, (2013) To evaluate the changes in the volume of rectovaginal endometriotic nodules infiltrating the rectum during 12-month treatment with hormonal therapies.This prospective, non-randomized, self-controlled ... |
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Gonadotropin-releasing hormone agonist for the prevention of chemotherapy-induced ovarian failure in patients with lymphoma: 1-year follow-up of a prospective randomized trial.
J. Clin. Oncol. 31(7) , 903-9, (2013) To assess the efficacy of gonadotropin-releasing hormone agonist (GnRHa) in preventing chemotherapy-induced ovarian failure in patients treated for Hodgkin or non-Hodgkin lymphoma within the setting o... |
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Adjuvant exemestane with ovarian suppression in premenopausal breast cancer.
N. Engl. J. Med. 371(2) , 107-18, (2014) Adjuvant therapy with an aromatase inhibitor improves outcomes, as compared with tamoxifen, in postmenopausal women with hormone-receptor-positive breast cancer.In two phase 3 trials, we randomly assi... |
| 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycinamide |
| triptorelinum |
| triptorelinum [INN_la] |
| Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolyl- |
| triptoreline |
| TRIPORELIN |
| MFCD00167541 |
| triptorelina |
| TRIPTORELIN AMIDE |
| UNII:9081Y98W2V |
| Triptorelin |
| TRIPTORELIN PAMOATE |
| Decapeptyl |
- DC Chemicals Limited
- China
- Product Name: Triptorelin
- Price: $250.0/100mg $500.0/250mg $1000.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Triptorelin Pamoate
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name:
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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