N-Succinimidyl 6-maleimidohexanoate

Modify Date: 2024-01-02 19:16:04

N-Succinimidyl 6-maleimidohexanoate Structure
N-Succinimidyl 6-maleimidohexanoate structure
Common Name N-Succinimidyl 6-maleimidohexanoate
CAS Number 55750-63-5 Molecular Weight 308.287
Density 1.4±0.1 g/cm3 Boiling Point 480.6±47.0 °C at 760 mmHg
Molecular Formula C14H16N2O6 Melting Point 70-73 °C(lit.)
MSDS Chinese USA Flash Point 244.5±29.3 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

 Use of N-Succinimidyl 6-maleimidohexanoate


6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates.

 Names

Name N-Succinimidyl 6-maleimidohexanoate
Synonym More Synonyms

 N-Succinimidyl 6-maleimidohexanoate Biological Activity

Description 6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates.
Related Catalog

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 480.6±47.0 °C at 760 mmHg
Melting Point 70-73 °C(lit.)
Molecular Formula C14H16N2O6
Molecular Weight 308.287
Flash Point 244.5±29.3 °C
Exact Mass 308.100830
PSA 101.06000
LogP -0.81
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.577
Storage condition −20°C
Water Solubility chloroform: 100mg/mL

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H315-H319-H335-H351
Precautionary Statements P280-P305 + P351 + P338-P337 + P313
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36/37-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2925190090

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles14

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Function of the Histone-Like Protein H-NS in Motility of Escherichia coli: Multiple Regulatory Roles Rather than Direct Action at the Flagellar Motor.

J. Bacteriol. 197 , 3110-20, (2015)

A number of investigations of Escherichia coli have suggested that the DNA-binding protein H-NS, in addition to its well-known functions in chromosome organization and gene regulation, interacts direc...

Successful acquisition of a neutralizing monoclonal antibody against a novel neutrophil-activating peptide, mitocryptide-1.

Biochem. Biophys. Res. Commun. 463 , 54-9, (2015)

Mitocryptide-1 (MCT-1) is a novel neutrophil-activating peptide derived from mitochondrial cytochrome c oxidase subunit VIII, and its physiological role and involvement in various diseases have not ye...

Moderate PEGylation of the carrier protein improves the polysaccharide-specific immunogenicity of meningococcal group A polysaccharide conjugate vaccine.

Vaccine 33 , 3208-14, (2015)

Neisseria meningitidis can cause severe and fulminant diseases such as meningitis. Meningococcal capsular polysaccharide (PS) is a key virulence determinant that is not able to induce immunological me...

 Synonyms

1-{6-[(2,5-Dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione
MFCD00043043
1-{6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione
1H-pyrrole-2,5-dione, 1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-
(2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate
N-succinimidyl-6-maleimidocaproate
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
MCOSU
EMCS