TRIETHYLENETETRAMINE DIHYDROCHLORIDE

Modify Date: 2024-01-13 09:21:35

TRIETHYLENETETRAMINE DIHYDROCHLORIDE Structure
TRIETHYLENETETRAMINE DIHYDROCHLORIDE structure
Common Name TRIETHYLENETETRAMINE DIHYDROCHLORIDE
CAS Number 38260-01-4 Molecular Weight 219.156
Density 0.958 g/cm3 Boiling Point 266.5ºC at 760 mmHg
Molecular Formula C6H20Cl2N4 Melting Point 120-125ºC (dec.)
MSDS Chinese USA Flash Point 143.3ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine,dihydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.958 g/cm3
Boiling Point 266.5ºC at 760 mmHg
Melting Point 120-125ºC (dec.)
Molecular Formula C6H20Cl2N4
Molecular Weight 219.156
Flash Point 143.3ºC
Exact Mass 218.106506
PSA 76.10000
LogP 1.86940

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KH8587085
CHEMICAL NAME :
1,2-Ethanediamine, N,N'-bis(2-aminoethyl)-, dihydrochloride
CAS REGISTRY NUMBER :
38260-01-4
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C6-H18-N4.2Cl-H
MOLECULAR WEIGHT :
219.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2285 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - other changes Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: (Suppl),246,1992 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
67500 mg/kg/90D-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Liver - fatty liver degeneration Blood - changes in spleen
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 29,185,1996 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1140 uL/kg
SEX/DURATION :
female 1-19 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
JNSVA5 Journal of Nutritional Science and Vitaminology. (Business Center for Academic Soc. Japan, 2-4-16 Yayoi, Bunkyo-ku, Tokyo 113, Japan) V.19- 1973- Volume(issue)/page/year: 38,545,1992
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
22800 mg/kg
SEX/DURATION :
female 1-19 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
JNSVA5 Journal of Nutritional Science and Vitaminology. (Business Center for Academic Soc. Japan, 2-4-16 Yayoi, Bunkyo-ku, Tokyo 113, Japan) V.19- 1973- Volume(issue)/page/year: 39,177,1993

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS KH8587085
HS Code 2921290000

 Synthetic Route

~78%

TRIETHYLENETETRAMINE DIHYDROCHLORIDE Structure

TRIETHYLENETETR...

CAS#:38260-01-4

Literature: Jonas, Marco; Vaulont, Irene; Soi, Antonio; Schmidt, Gunther Patent: US2006/41170 A1, 2006 ; Location in patent: Page/Page column 28 ;

~82%

TRIETHYLENETETRAMINE DIHYDROCHLORIDE Structure

TRIETHYLENETETR...

CAS#:38260-01-4

Literature: Jonas, Marco; Vaulont, Irene; Soi, Antonio; Schmidt, Gunther Patent: US2006/41170 A1, 2006 ; Location in patent: Page/Page column 21 ;

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2921290000
Summary 2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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 Synonyms

EINECS 253-854-3
MK-0681
Triethylenetetramine dihydrochloride
N,N'-bis(2-aminoéthyl)éthane-1,2-diamine dichlorhydrate
Trien dihydrochloride
Syprine
N,N'-Bis(2-aminoethyl)-1,2-ethanediamine dihydrochloride
Trientine hydrochloride
MFCD00012889
n,n'-bis(2-aminoethyl)ethan-1,2-diamindihydrochlorid
1,2-Ethanediamine, N,N-bis(2-aminoethyl)-, hydrochloride (1:2)
N,N'-Bis(2-aminoethyl)ethane-1,2-diamine dihydrochloride
trientine dihydrochloride
Triethylenetetraamine dihydrochloride