(R)-(-)-NIPECOTIC ACID ETHYL ESTER

Modify Date: 2024-01-02 21:52:06

(R)-(-)-NIPECOTIC ACID ETHYL ESTER Structure
(R)-(-)-NIPECOTIC ACID ETHYL ESTER structure
Common Name (R)-(-)-NIPECOTIC ACID ETHYL ESTER
CAS Number 25137-01-3 Molecular Weight 157.210
Density 1.0±0.1 g/cm3 Boiling Point 238.6±0.0 °C at 760 mmHg
Molecular Formula C8H15NO2 Melting Point N/A
MSDS Chinese USA Flash Point 90.6±0.0 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

Name Ethyl (3R)-piperidine-3-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 238.6±0.0 °C at 760 mmHg
Molecular Formula C8H15NO2
Molecular Weight 157.210
Flash Point 90.6±0.0 °C
Exact Mass 157.110275
PSA 38.33000
LogP 0.96
Vapour Pressure 0.0±0.4 mmHg at 25°C
Index of Refraction 1.449
Storage condition Refrigerator

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H315-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38-41-37/38
Safety Phrases S26-S36/37/39-S39-S36
RIDADR NONH for all modes of transport
HS Code 2933399090

 Synthetic Route

~20%

(R)-(-)-NIPECOTIC ACID ETHYL ESTER Structure

(R)-(-)-NIPECOT...

CAS#:25137-01-3

Literature: Yamanaka, Toshio; Ohkubo, Mitsuru; Takahashi, Fumie; Kato, Masayuki Tetrahedron Letters, 2004 , vol. 45, # 13 p. 2843 - 2845

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(R)-(-)-NIPECOTIC ACID ETHYL ESTER Structure

(R)-(-)-NIPECOT...

CAS#:25137-01-3

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 70, p. 899,913 Chemische Berichte, , vol. 102, p. 2864 Gazzetta Chimica Italiana, , vol. 102, p. 189,190, 192, 193

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(R)-(-)-NIPECOTIC ACID ETHYL ESTER Structure

(R)-(-)-NIPECOT...

CAS#:25137-01-3

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 70, p. 899,913

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles7

More Articles
THIP analgesia: cross tolerance with morphine.

Life Sci. 32(19) , 2265-72, (1983)

THIP (4,5,6,7-tetrahydroisoxazolo (5,4-c) pyridone-3-ol), a direct acting GABA receptor agonist, has been shown to have antinociceptive properties. To determine whether tolerance develops to the analg...

(R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors.

J. Pharmacol. Exp. Ther. 242(1) , 173-8, (1987)

Previous reports have suggested that the ethyl ester of (R)-nipecotic acid ethyl ester [(R)-NAEE] displays cholinomimetic properties in vivo. The present study was undertaken to characterize more full...

Differential effects of ethyl (R,S)-nipecotate on the behaviors of highly and minimally aggressive female golden hamsters.

Psychopharmacology 89(4) , 444-8, (1986)

The GABA uptake inhibitor ethyl (R,S)-nipecotate produces a dose-dependent suppression of aggression in highly aggressive hamsters but not in minimally aggressive ones. This suppression occurs at dose...

 Synonyms

(R)-Ethyl nipecotate
Ethyl (R)-3-Piperidinecarboxylate
(R)-Ethylpiperidine-3-carboxylate
Ethyl (R)-nipecotate
(R)-(-)-Nipecotic Acid Ethyl Ester
(R)-(-)-Ethyl nipecotate
(R)-Nipecotic acid ethyl ester
ethyl R-nipecotate
Ethyl (R)-(-)-piperidine-3-carboxylate
(R)-(-)-3-Piperidinecarboxylic Acid Ethyl Ester
3-Piperidinecarboxylic acid, ethyl ester, (3R)-
Ethyl (R)-(-)-3-Piperidinecarboxylate
Ethyl (R)-(-)-Nipecotate
MFCD03093637
Ethyl (3R)-3-piperidinecarboxylate
Ethyl (3R)-piperidine-3-carboxylate
(R)-Ethyl piperidine-3-carboxylate
D-Nipecotic acid ethyl ester
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