thiouridine

Modify Date: 2024-01-02 21:37:35

thiouridine structure	Common Name	thiouridine
	CAS Number	20235-78-3	Molecular Weight	260.267
	Density	1.7±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₉H₁₂N₂O₅S	Melting Point	216-218ºC
	MSDS	N/A	Flash Point	N/A

Use of thiouridine

2-Thiouridine (s2U) is a modified nucleobase found in tRNAs that is known to stabilize U:A pairs and modestly destabilize U:G wobble pairs.

Name	2-Thiouridine
Synonym	More Synonyms

Density	1.7±0.1 g/cm3
Melting Point	216-218ºC
Molecular Formula	C₉H₁₂N₂O₅S
Molecular Weight	260.267
Exact Mass	260.046692
PSA	139.80000
LogP	-0.96
Index of Refraction	1.733
Storage condition	Refrigerator

2’,3’,5’-Tri-O-...

CAS#:21052-18-6

~90%

thiouridine

CAS#:20235-78-3

Literature: El-Tayeb, Ali; Qi, Aidong; Mueller, Christa E. Journal of Medicinal Chemistry, 2006 , vol. 49, # 24 p. 7076 - 7087

b-D-Ribofuranos...

CAS#:6974-32-9

~85%

thiouridine

CAS#:20235-78-3

Literature: Sierzputowska-Gracz; Sochacka; Malkiewicz; Kuo; Gehrke; Agris Journal of the American Chemical Society, 1987 , vol. 109, # 23 p. 7171 - 7177

4-methylsulfany...

CAS#:25030-30-2

~65%

thiouridine

CAS#:20235-78-3

Literature: Robin, Aelig; Julienne, Karine; Meslin, Jean-Claude; Deniaud, David European Journal of Organic Chemistry, 2006 , # 3 p. 634 - 643

1-(2,3,5-tri-O-...

CAS#:627812-08-2

thiouridine

CAS#:20235-78-3

Literature: European Journal of Organic Chemistry, , # 3 p. 634 - 643

2',3'-O-Isoprop...

CAS#:6984-55-0

thiouridine

CAS#:20235-78-3

Literature: Journal of the Chemical Society, , p. 3028,3033

2,3,5-Tri-O-ben...

CAS#:7408-41-5

thiouridine

CAS#:20235-78-3

Literature: Journal of the Chemical Society, , p. 2294,2297

2-methoxyuridine

CAS#:53337-88-5

4-thiouridine

CAS#:13957-31-8

thiouridine

CAS#:20235-78-3

Literature: Journal of Heterocyclic Chemistry, , vol. 17, p. 1601 - 1602

4-ethoxy-1-(β-D...

CAS#:59495-20-4

4-thiouridine

CAS#:13957-31-8

thiouridine

CAS#:20235-78-3

Literature: Journal of Heterocyclic Chemistry, , vol. 17, p. 1601 - 1602

2',3'-O-isoprop...

CAS#:3868-21-1

thiouridine

CAS#:20235-78-3

Literature: Journal of the Chemical Society, , p. 3028,3033

Precursor 7
CAS#:21052-18-6 2’,3’,5’-Tri-O-... CAS#:6974-32-9 b-D-Ribofuranos... CAS#:25030-30-2 4-methylsulfany... CAS#:627812-08-2 1-(2,3,5-tri-O-...
CAS#:7408-41-5 2,3,5-Tri-O-ben... CAS#:59495-20-4 4-ethoxy-1-(β-D... CAS#:3868-21-1 2',3'-O-isoprop...
DownStream 3
CAS#:58-96-8 Uridine CAS#:29123-25-9 2-Thiouridine 5... CAS#:35763-29-2 2-Thiouridine5'...

1-(β-D-Ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone

4(1H)-Pyrimidinone, 2,3-dihydro-1-β-D-ribofuranosyl-2-thioxo-

2-Thiouridine

2-thiouridine—

thiouridine

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one

thiouridine

Use of thiouridine

Names

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms