Propachlor

Modify Date: 2024-01-04 19:21:00

Propachlor structure	Common Name	Propachlor
	CAS Number	1918-16-7	Molecular Weight	211.688
	Density	1.1±0.1 g/cm3	Boiling Point	290.4±23.0 °C at 760 mmHg
	Molecular Formula	C₁₁H₁₄ClNO	Melting Point	67-76°C
	MSDS	Chinese USA	Flash Point	129.4±22.6 °C
	Symbol	GHS07, GHS09	Signal Word	Warning

Use of Propachlor

Propachlor is a specific ALDH1A1 inhibitor. It is sometimes used as an herbicide.

Name	propachlor
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	290.4±23.0 °C at 760 mmHg
Melting Point	67-76°C
Molecular Formula	C₁₁H₁₄ClNO
Molecular Weight	211.688
Flash Point	129.4±22.6 °C
Exact Mass	211.076385
PSA	20.31000
LogP	2.28
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.551

Propachlor MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AE1575000

CHEMICAL NAME :: Acetanilide, 2-chloro-N-isopropyl-

CAS REGISTRY NUMBER :: 1918-16-7

LAST UPDATED :: 199806

DATA ITEMS CITED :: 20

MOLECULAR FORMULA :: C11-H14-Cl-N-O

MOLECULAR WEIGHT :: 211.71

WISWESSER LINE NOTATION :: G1VNR&Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 710 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1056 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 290 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 306 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 392 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 380 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 91 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 512 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3458 mg/kg/26W-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1400 mg/kg/20D-I

TOXIC EFFECTS :: Liver - liver function tests impaired Blood - pigmented or nucleated red blood cells Biochemical - Metabolism (Intermediary) - other proteins

TYPE OF TEST :: Mutation test systems - not otherwise specified

TYPE OF TEST :: Sperm Morphology

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 10 mg/kg

REFERENCE :: CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 14(6),38,1980 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H317-H319-H410
Precautionary Statements	P273-P280-P305 + P351 + P338-P501
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful;N:Dangerousfortheenvironment;
Risk Phrases	R22;R36;R43;R50/53
Safety Phrases	S24-S37-S60-S61
RIDADR	UN 2811
RTECS	AE1575000
HS Code	2924299014

Precursor 2
CAS#:768-52-5 N-Isopropylaniline CAS#:79-04-9 Chloroacetyl ch...
DownStream 2
CAS#:768-52-5 N-Isopropylaniline CAS#:10487-31-7 1-ISOPROPYL-1H-...

HS Code	2924299014
Summary	2924299014 2-chloro-n-isopropyl-n-phenylacetamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

Glutathione-dependent cytotoxicity of the chloroacetanilide herbicides alachlor, metolachlor, and propachlor in rat and human hepatoma-derived cultured cells.

Cell Biol. Toxicol. 15(5) , 325-32, (1999)

Alachlor, metolachlor, and propachlor are widely used chloroacetanilide herbicides. Their cytotoxicity in rat (Fa32) and human (Hep G2) hepatoma-derived cells was investigated, in connection with thei...

Kinetics and mechanism of propachlor reductive transformation through nucleophilic substitution by dithionite

Chemosphere 85(9) , 1438-43, (2011)

Highlights ► The reductive dechlorination of propachlor was efficiently achieved by dithionite. ► The transformation of propachlor initiated by dithionite follows second-order kinetics. ► Dechlorinati...

Characterization of glutathione conjugates of chloroacetanilide pesticides using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and liquid chromatography/ion trap mass spectrometry.

Rapid Commun. Mass Spectrom. 21(24) , 4017-22, (2007)

Glutathione S-transferases (GSTs) isolated from maize were used to catalyze the conjugation of glutathione (GSH) with chloroacetanilide herbicides, producing stable conjugates that were structurally c...

2-Chloro-N-isopropylacetanilide

Satecid

N-isopropyl-2-chloroacetanilide

2-Chloro-N-isopropyl-N-phenyl-acetamide

Niticid

N-isopropyl-N-phenyl-chloroacetamide

2-Chloro-N-isopropyl-N-phenylacetamide

Prolex

Propachlore

2-Chloro-N-(1-methylethyl)-N-phenylacetamide (9CI)

Nitacid

α-chloro-N-isopropylacetanilide

MFCD00078731

EINECS 217-638-2

Bexton

2-chloro-N-(1-methylethyl)-N-phenylacetamide

2-chloro-N-phenyl-N-(propan-2-yl)acetamide

n-isopropyl-a-chloroacetanilide

Bexton 4L

2-chloro-N-phenyl-N-propan-2-ylacetamide

Acetamide, 2-chloro-N-(1-methylethyl)-N-phenyl-

Ramrod

Propachlor

DC Chemicals Limited
China
Product Name: Acilid
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Propachlor

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