PF-06456384

Modify Date: 2024-01-09 13:25:32

PF-06456384 structure	Common Name	PF-06456384
	CAS Number	1834610-73-9	Molecular Weight	719.80
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₅H₃₂F₃N₇O₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PF-06456384

PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 can be used for parkinson's disease (PD) research[1].

Name	PF-06456384

Description	PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 can be used for parkinson's disease (PD) research[1].
Related Catalog	Signaling Pathways >> Autophagy >> LRRK2 Research Areas >> Neurological Disease
References	[1]. Jaclyn L Henderson, et al. Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Jan 8;58(1):419-32.

Molecular Formula	C₃₅H₃₂F₃N₇O₃S₂
Molecular Weight	719.80

DC Chemicals Limited
China
Product Name: PF-06456384
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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