Tyrphostin AG 1478

Modify Date: 2024-01-02 20:06:53

Tyrphostin AG 1478 Structure
Tyrphostin AG 1478 structure
Common Name Tyrphostin AG 1478
CAS Number 175178-82-2 Molecular Weight 315.754
Density 1.3±0.1 g/cm3 Boiling Point 458.5±45.0 °C at 760 mmHg
Molecular Formula C16H14ClN3O2 Melting Point N/A
MSDS USA Flash Point 231.1±28.7 °C

 Names

Name ag 1478
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 458.5±45.0 °C at 760 mmHg
Molecular Formula C16H14ClN3O2
Molecular Weight 315.754
Flash Point 231.1±28.7 °C
Exact Mass 315.077454
PSA 56.27000
LogP 3.77
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.668
Storage condition 2-8°C
Water Solubility 0.1 M HCl: soluble <0.4 mg/mL

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles19

More Articles
HuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration.

Br. J. Pharmacol. 172 , 3028-42, (2015)

Angiotensin II (AngII) and IL-1β are involved in cardiovascular diseases through the induction of inflammatory pathways. HuR is an adenylate- and uridylate-rich element (ARE)-binding protein involved ...

Regulatory volume increase in astrocytes exposed to hypertonic medium requires β1 -adrenergic Na(+) /K(+) -ATPase stimulation and glycogenolysis.

J. Neurosci. Res. 93(1) , 130-9, (2014)

The cotransporter of Na(+) , K(+) , 2Cl(-) , and water, NKKC1, is activated under two conditions in the brain, exposure to highly elevated extracellular K(+) concentrations, causing astrocytic swellin...

Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.

BMC Cancer 11 , 421, (2011)

Neurotensin has been found to promote colon carcinogenesis in rats and mice, and proliferation of human colon carcinoma cell lines, but the mechanisms involved are not clear. We have examined signalli...

 Synonyms

n-(3-chlorphenyl)-6,7-dimethoxy-4-chinazolinamin
4-Quinazolinamine, N-(3-chlorophenyl)-6,7-dimethoxy-
Tyrphostin AG 1478
4-(3-Chloro-benzyl)-6,7-dimethoxy-quinazoline
MFCD00270914
N-(3-Chlorophenyl)-6,7-dimethoxyquinazolin-4-amine