Fmoc-D-Trp(Boc)-OH

Modify Date: 2024-01-02 17:47:53

Fmoc-D-Trp(Boc)-OH Structure
Fmoc-D-Trp(Boc)-OH structure
Common Name Fmoc-D-Trp(Boc)-OH
CAS Number 163619-04-3 Molecular Weight 526.580
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C31H30N2O6 Melting Point 86 - 92ºC (Decomposes)
MSDS Chinese USA Flash Point N/A

 Use of Fmoc-D-Trp(Boc)-OH


Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).

 Names

Name (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
Synonym More Synonyms

 Fmoc-D-Trp(Boc)-OH Biological Activity

Description Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Melting Point 86 - 92ºC (Decomposes)
Molecular Formula C31H30N2O6
Molecular Weight 526.580
Exact Mass 526.210388
PSA 106.86000
LogP 7.05
Index of Refraction 1.632
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles1

More Articles
Solid-phase synthesis of C-terminal azapeptides.

J. Pept. Sci. 21 , 387-91, (2015)

The solid-phase synthesis of azapeptides possessing a C-terminal aza-residue has been accomplished by a protocol featuring regioselective alkylation of benzhydrylidene-aza-glycinamide and illustrated ...

 Synonyms

1-(tert-Butoxycarbonyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tryptophan
Nalpha-Fmoc-N(in)-Boc-D-tryptophan
AmbotzFAA1339
Fmoc-D-Trp(Boc)
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-tryptophan
D-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
Fmoc-D-Trp(Boc)-OH
N|A-Fmoc-N(in)-Boc-D-tryptophan
Fmoc-L-Trp(Boc)-OH
MFCD00153367
(2R)-3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid
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