Adenosine-5'-diphosphate disodium salt

Modify Date: 2024-01-02 16:21:29

Adenosine-5'-diphosphate disodium salt Structure
Adenosine-5'-diphosphate disodium salt structure
Common Name Adenosine-5'-diphosphate disodium salt
CAS Number 16178-48-6 Molecular Weight 471.165
Density N/A Boiling Point 877.7ºC at 760 mmHg
Molecular Formula C10H13N5Na2O10P2 Melting Point N/A
MSDS USA Flash Point 484.6ºC

 Use of Adenosine-5'-diphosphate disodium salt


Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis[1][2].

 Names

Name Adenosine-5'-diphosphate disodium salt
Synonym More Synonyms

 Adenosine-5'-diphosphate disodium salt Biological Activity

Description Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis[1][2].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Adenosine 5'-diphosphate disodium (10 μmol/L) 诱导人血小板聚集以及血小板,B10 细胞和 p2y1 转染细胞中的 [Ca2+]i 的增加[1]。 Adenosine 5'-diphosphate disodium (5 μmol/L) 可提高人血小板和 B10 细胞中 cAMP 的水平[1]。
References

[1]. Hechler B, et al. The P2Y1 receptor is necessary for adenosine 5'-diphosphate-induced platelet aggregation. Blood. 1998 Jul 1;92(1):152-9.  

[2]. Arts IC, et al. Adenosine 5'-triphosphate (ATP) supplements are not orally bioavailable: a randomized, placebo-controlled cross-over trial in healthy humans. J Int Soc Sports Nutr. 2012 Apr 17;9(1):16.  

 Chemical & Physical Properties

Boiling Point 877.7ºC at 760 mmHg
Molecular Formula C10H13N5Na2O10P2
Molecular Weight 471.165
Flash Point 484.6ºC
Exact Mass 470.993317
PSA 257.88000
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles5

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Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist.

Arterioscler. Thromb. Vasc. Biol. 31 , 416-422, (2011)

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Extracellular Ca(2+) modulates ADP-evoked aggregation through altered agonist degradation: implications for conditions used to study P2Y receptor activation.

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 Synonyms

Adenosine 5'-Diphosphate Disodium Salt Hydrate
EINECS 240-314-7
adenosine diphosphate sodium salt
Adenosine 5′-diphosphate disodium salt
5'-ADP-Na2
Adenosine 5'-diphosphate disodium salt
5'-ADP Na Hydrate
Adenosine, 5'-(trihydrogen diphosphate), sodium salt (1:2)
Disodium 5'-O-{[(hydroxyphosphinato)oxy]phosphinato}adenosine
Adenosine 5‘-diphosphate,disodium salt hydrate
MFCD00066635
Adenosine-5'-diphosphatedisodiumsalt
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