Fexofenadine hydrochloride

Modify Date: 2024-01-02 17:16:23

Fexofenadine hydrochloride Structure
Fexofenadine hydrochloride structure
Common Name Fexofenadine hydrochloride
CAS Number 153439-40-8 Molecular Weight 538.117
Density N/A Boiling Point N/A
Molecular Formula C32H40ClNO4 Melting Point 148-150oC
MSDS USA Flash Point N/A

 Use of Fexofenadine hydrochloride


Fexofenadine is a third-generation antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria.

 Names

Name Fexofenadine Hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Melting Point 148-150oC
Molecular Formula C32H40ClNO4
Molecular Weight 538.117
Exact Mass 537.264587
PSA 81.00000
LogP 6.25040
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport

 Articles12

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Histamine inhibits differentiation of skin fibroblasts into myofibroblasts.

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Histamine and TGF-β, major mediators secreted by mast cells, are involved in skin inflammation and play critical roles in the pathogenesis of systemic sclerosis. However, the roles of signaling mechan...

Probiotic properties of lactic acid bacteria isolated from water-buffalo mozzarella cheese.

Probiotics Antimicrob Proteins 6 , 141-56, (2014)

This study evaluated the probiotic properties (stability at different pH values and bile salt concentration, auto-aggregation and co-aggregation, survival in the presence of antibiotics and commercial...

Substrate- and dose-dependent drug interactions with grapefruit juice caused by multiple binding sites on OATP2B1.

Pharm. Res. 31(8) , 2035-43, (2014)

OATP2B1-mediated grapefruit juice (GFJ)-drug interactions are substrate-dependent; for example, GFJ ingestion significantly reduces bioavailability of fexofenadine, but not pravastatin. In the present...

 Synonyms

2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butyl)phenyl]-2-methylpropansäurehydrochlorid
Fexofenidine hydrochloride MDL 16455 hydrochloride Terfenidine carboxylate hydrochloride
Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride (1:1)
Fexofenadine HCl
Fexofenadine hydrochloride
benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride
Fexofenidine hydrochloride,MDL 16455 hydrochloride,Terfenidine carboxylate hydrochloride
2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butyl)phenyl]-2-methylpropanoic acid hydrochloride (1:1)
acide 2-[4-(1-hydroxy-4-{4-[hydroxy(diphényl)méthyl]pipéridin-1-yl}butyl)phényl]-2-méthylpropanoïque chlorhydrate
MFCD08064193
UNII:2S068B75ZU
2-[4-(1-hydroxy-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butyl)phenyl]-2-methylpropanoic acid hydrochloride
2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]-1-piperidinyl}butyl)phenyl]-2-methylpropanoic acid hydrochloride (1:1)
benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-a,a-dimethyl-, hydrochloride (1:1)
Benzeneacetic acid, 4-​[1-​hydroxy-​4-​[4-​(hydroxydiphenylmeth​yl)​-​1-​piperidinyl]​butyl]​-​α,​α-​dimethyl-​, hydrochloride
Fexofenadine (hydrochloride)
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