Propargyl-PEG1-SS-alcohol

Modify Date: 2024-01-08 19:35:19

Propargyl-PEG1-SS-alcohol Structure
Propargyl-PEG1-SS-alcohol structure
Common Name Propargyl-PEG1-SS-alcohol
CAS Number 1391914-41-2 Molecular Weight 192.299
Density 1.2±0.1 g/cm3 Boiling Point 319.2±32.0 °C at 760 mmHg
Molecular Formula C7H12O2S2 Melting Point N/A
MSDS N/A Flash Point 146.8±25.1 °C

 Use of Propargyl-PEG1-SS-alcohol


Propargyl-PEG1-SS-alcohol is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Propargyl-PEG1-SS-alcohol
Synonym More Synonyms

 Propargyl-PEG1-SS-alcohol Biological Activity

Description Propargyl-PEG1-SS-alcohol is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 319.2±32.0 °C at 760 mmHg
Molecular Formula C7H12O2S2
Molecular Weight 192.299
Flash Point 146.8±25.1 °C
Exact Mass 192.027863
LogP 1.70
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.559

 Synonyms

2-{[2-(2-Propyn-1-yloxy)ethyl]disulfanyl}ethanol
Ethanol, 2-[[2-(2-propyn-1-yloxy)ethyl]dithio]-
MFCD28505558