1H-Imidazole-4-carboxylic acid

Modify Date: 2024-01-02 12:31:10

1H-Imidazole-4-carboxylic acid Structure
1H-Imidazole-4-carboxylic acid structure
Common Name 1H-Imidazole-4-carboxylic acid
CAS Number 1072-84-0 Molecular Weight 112.09
Density 1.5±0.1 g/cm3 Boiling Point 495.0±18.0 °C at 760 mmHg
Molecular Formula C4H4N2O2 Melting Point 294-295 °C(lit.)
MSDS Chinese USA Flash Point 253.2±21.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 1H-Imidazole-4-carboxylic acid


1H-Imidazole-4-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 1H-Imidazole-4-carboxylic acid
Synonym More Synonyms

 1H-Imidazole-4-carboxylic acid Biological Activity

Description 1H-Imidazole-4-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 495.0±18.0 °C at 760 mmHg
Melting Point 294-295 °C(lit.)
Molecular Formula C4H4N2O2
Molecular Weight 112.09
Flash Point 253.2±21.2 °C
Exact Mass 112.027275
PSA 65.98000
LogP 0.46
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.617
Storage condition Refrigerator

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NI4001000
CHEMICAL NAME :
Imidazole-4-carboxylic acid
CAS REGISTRY NUMBER :
1072-84-0
LAST UPDATED :
198709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C4-H4-N2-O2
MOLECULAR WEIGHT :
112.10
WISWESSER LINE NOTATION :
T5M CNJ DVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PBPHAW Progress in Biochemical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1965- Volume(issue)/page/year: 1,542,1965

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS NI4001000
HS Code 2933290090

 Synthetic Route

~94%

1H-Imidazole-4-carboxylic acid Structure

1H-Imidazole-4-...

CAS#:1072-84-0

Literature: Sloboda-Rozner, Dorit; Witte, Peter; Alsters, Paul L.; Neumann, Ronny Advanced Synthesis and Catalysis, 2004 , vol. 346, # 2-3 p. 339 - 345

~88%

1H-Imidazole-4-carboxylic acid Structure

1H-Imidazole-4-...

CAS#:1072-84-0

Literature: Gadakh, Amol V.; Chikanna, Dinesh; Rindhe, Sahebrao S.; Karale, Bhausaheb K. Synthetic Communications, 2012 , vol. 42, # 5 p. 658 - 666

~%

1H-Imidazole-4-carboxylic acid Structure

1H-Imidazole-4-...

CAS#:1072-84-0

Literature: US4672128 A1, ;

~78%

1H-Imidazole-4-carboxylic acid Structure

1H-Imidazole-4-...

CAS#:1072-84-0

Literature: Davis, Dwight P.; Kirk, Kenneth L.; Cohen, Louis A. Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 253 - 256

~84%

1H-Imidazole-4-carboxylic acid Structure

1H-Imidazole-4-...

CAS#:1072-84-0

Literature: Piotrovskii, L. B.; Dumpis, M. A.; Shabanov, P. D. Pharmaceutical Chemistry Journal, 1986 , vol. 20, # 7 p. 460 - 463 Khimiko-Farmatsevticheskii Zhurnal, 1986 , vol. 20, # 7 p. 799 - 802

~%

1H-Imidazole-4-carboxylic acid Structure

1H-Imidazole-4-...

CAS#:1072-84-0

Literature: EP1196129 B1, ; Page/Page column 5; 14; 15; 22 ;

~%

1H-Imidazole-4-carboxylic acid Structure

1H-Imidazole-4-...

CAS#:1072-84-0

Detail
Literature: EP1196129 B1, ; Page/Page column 4; 5; 7; 8; 21; 22 ;

 Customs

HS Code 2933290090
Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles8

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Vet. J. 205 , 381-6, (2015)

Equine metabolic syndrome is characterized by obesity and insulin resistance (IR). Currently, there is no effective pharmacological treatment for this insidious disease. Glucose uptake is mediated by ...

Hair analysis of histamine and several metabolites in C3H/HeNCrj mice by ultra performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry (UPLC-ESI-TOF-MS): influence of hair cycle and age.

Clin. Chim. Acta 378(1-2) , 122-7, (2007)

According to a previous study, the concentration of HA in the hair of SD rats was similar in each rat and the variation in HA concentration was not so great. However, the concentration in human hair w...

Phosphate ester hydrolysis by hydroxo complexes of trivalent lanthanides stabilized by 4-imidazolecarboxylate.

Inorg. Chem. 45(23) , 9502-17, (2006)

The anion of 4-imidazolecarboxylic acid (HL) stabilizes hydroxo complexes of trivalent lanthanides of the type ML(OH)+ (M = La, Pr) and M2L(n)(OH)(6-n) (M = La, n = 2; M = Pr, n = 2, 3; M = Nd, Eu, Dy...

 Synonyms

4-IMidazolecarboxylic Acid
IMIDAZOLE-4-CARBOXYLIC ACID
1H-imidazol-4-ylcarboxylic acid
MFCD00082203
1H-Imidazole-5-carboxylic acid
4,5-imidazoledicarboxylic acid
Imidazol-4-carboxylic acid
RARECHEM AL BE 0762
4-hydroxy imizodale
4-carboxyimidazole
1H-Imidazole-4-carboxylic acid
EINECS 214-017-8
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