DC Chemicals Limited
China
Product Name: Zotarolimus
Price: $500.0/100mg $1000.0/250mg $2000.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

221877-54-9

221877-54-9 structure

221877-54-9 structure

Name: Zotarolimus
Chemical Name: Zotarolimus
CAS Number: 221877-54-9
Molecular Formula: C₅₂H₇₉N₅O₁₂
Molecular Weight: 966.210
Catalog: Biochemical Inhibitor PI3K/Akt/mTOR inhibitor (PI3K/Akt/mTOR) mTOR inhibitor
Create Date: 2018-08-26 11:20:13
Modify Date: 2024-01-02 17:46:43
Zotarolimus is a tetrazole-containing Rapamycin analog which is used as animmunomodulator, and is useful in the treatment of restenosis, immune, and autoimmune diseases.

Name	Zotarolimus
Synonyms	(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-19,30-dimethoxy-12-{(2R)-1-[(1S,3R,4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]-2-propanyl}-15,17,21,23,29,35-hexamethyl-11, ;36-dioxa-4-azatricyclo[30.3.1.0]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-10,21-dimethoxy-3-[(1R)-2-[(1S,3R,4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]-1-methylethyl]-6,8,12,14,20,26-hexamethyl-, (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)- (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-10,21-dimethoxy-3-{(2R)-1-[(1S,3R,4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]propan-2-yl}-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone Zotarolimus ABT-578

Description	Zotarolimus is a tetrazole-containing Rapamycin analog which is used as animmunomodulator, and is useful in the treatment of restenosis, immune, and autoimmune diseases.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
References	[1]. Wagner R et al. Rapamycin analogs with reduced systemic exposure. et al. Bioorg Med Chem Lett. 2005 Dec 1, 15(23), 5340-3.

Density	1.3±0.1 g/cm3
Boiling Point	1016.2±75.0 °C at 760 mmHg
Melting Point	100-105°C
Molecular Formula	C₅₂H₇₉N₅O₁₂
Molecular Weight	966.210
Flash Point	568.4±37.1 °C
Exact Mass	965.572510
PSA	218.80000
LogP	3.55
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.586
Storage condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere

HS Code	29349990