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7054-11-7

7054-11-7 structure
7054-11-7 structure
  • Name: CHLORPHENAMINE MALEATES
  • Chemical Name: chlorpheniramine maleate
  • CAS Number: 7054-11-7
  • Molecular Formula: C20H23ClN2O4
  • Molecular Weight: 390.86100
  • Create Date: 2018-12-30 15:05:39
  • Modify Date: 2024-01-04 16:31:44

Name chlorpheniramine maleate
Synonyms chlorphenamine maleate
chloropheniramine maleate
chlortrimeton
Melting Point 130-135ºC(lit.)
Molecular Formula C20H23ClN2O4
Molecular Weight 390.86100
Exact Mass 390.13500
PSA 90.73000
LogP 3.14170

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US6503000
CAS REGISTRY NUMBER :
7054-11-7
LAST UPDATED :
199806
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C16-H19-Cl-N2.C4-H4-O4
MOLECULAR WEIGHT :
390.90
WISWESSER LINE NOTATION :
T6NJ BYR DG&2N1&1 &QV1U1VQ -+-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
118 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
89 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
121 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
73 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
265 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - rat Liver
DOSE/DURATION :
500 umol/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 24,181,1994
Hazard Codes T,Xi
Risk Phrases 25-36/37/38
Safety Phrases 36/37/39-45-36-26
RIDADR UN 2811 6.1/PG 3