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133-65-3

133-65-3 structure
133-65-3 structure

Name solasulfone
Synonyms EINECS 205-116-7
RP 3668
Solapsone
Cimedone
sulphetrone
sulfetrone
Molecular Formula C30H28N2Na4O14S5
Molecular Weight 892.83200
Exact Mass 891.97300
PSA 328.90000
LogP 7.98900

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TZ2580000
CHEMICAL NAME :
1,3-Propanedisulfonic acid, 1,1'-(sulfonylbis(p-phenyleneimino))bis(3-phenyl-, tetrasodium salt
CAS REGISTRY NUMBER :
133-65-3
LAST UPDATED :
199512
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C30-H28-N2-O14-S5.4Na
MOLECULAR WEIGHT :
892.86
WISWESSER LINE NOTATION :
WSO&YR&1YSWO&MR DSWR DMYSWO&1YR&SWO &-NA- 4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,213,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARTUA4 American Review of Tuberculosis. (New York, NY) V.1-70, 1917-54. For publisher information, see ARDSBL. Volume(issue)/page/year: 60,62,1949
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2700 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 3,15,1948 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
48 mg/kg/40D-C
TOXIC EFFECTS :
Blood - microcytosis with or without anemia Related to Chronic Data - death
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 3,15,1948