Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1-tert-butyl-4,4-diphenylpiperidine
Price: ￥6276.0/1g ￥2506.0/250mg
Purity: 95.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Budipine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

57982-78-2

57982-78-2 structure

57982-78-2 structure

Name: 1-tert-butyl-4,4-diphenylpiperidine
Chemical Name: 1-tert-Butyl-4,4-diphenyl-piperidine
CAS Number: 57982-78-2
Molecular Formula: C₂₁H₂₇N
Molecular Weight: 293.446
Catalog: API Nervous system medication Anti-shock palsy
Create Date: 2018-03-04 08:00:00
Modify Date: 2024-01-01 20:45:52
Budipine is an antiparkinsonian agent.

Name	1-tert-Butyl-4,4-diphenyl-piperidine
Synonyms	Piperidine, 1-(1,1-dimethylethyl)-4,4-diphenyl- 1-(1,1-Dimethylethyl)-4,4-diphenyl-piperidine 1-tert-butyl-4,4-diphenylpiperidine 1-(2-Methyl-2-propanyl)-4,4-diphenylpiperidine

Description	Budipine is an antiparkinsonian agent.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Reichmann H, et al. Budipine in Parkinson's tremor. J Neurol Sci. 2006 Oct 25;248(1-2):53-5.

Density	1.0±0.1 g/cm3
Boiling Point	387.6±42.0 °C at 760 mmHg
Melting Point	108.5°C
Molecular Formula	C₂₁H₂₇N
Molecular Weight	293.446
Flash Point	168.7±24.8 °C
Exact Mass	293.214355
PSA	3.24000
LogP	4.64
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.558

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM7291100

CHEMICAL NAME :: Piperidine, 1-(1,1-dimethylethyl)-4,4-diphenyl-

CAS REGISTRY NUMBER :: 57982-78-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C21-H27-N

MOLECULAR WEIGHT :: 293.49

WISWESSER LINE NOTATION :: T6NTJ AX1&1&1 DR& DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 165 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,85,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,85,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,85,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 33 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,85,1982

HS Code	2933399090

1465-76-5 structure

1465-76-5

71-43-2 structure

71-43-2

~%

57982-78-2 structure

57982-78-2

Literature: Arzneimittel-Forschung/Drug Research, , vol. 34, # 3 p. 233 - 240

Precursor 2
1465-76-5 71-43-2
DownStream 0

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%