BioBioPha
China
Product Name: Isodorsmanin A
Price: ￥3500.0/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

118266-99-2

118266-99-2 structure

118266-99-2 structure

Name: crotmadine
Chemical Name: Isodorsmanin A
CAS Number: 118266-99-2
Molecular Formula: C₂₀H₂₀O₄
Molecular Weight: 324.37
Catalog: Natural product Chalcone
Create Date: 2016-11-04 21:45:46
Modify Date: 2024-03-11 10:15:59
Isodorsmanin A is an anti-inflammatory agent. Isodorsmanin A suppresses the production of inflammatory mediators and proinflammatory cytokines. Isodorsmanin A inhibits the phosphorylation of JNK, MAPK[1].

Name	Isodorsmanin A
Synonyms	(2E)-1-(5-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-8-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one 2-Propen-1-one, 1-(3,4-dihydro-5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-(4-hydroxyphenyl)-, (2E)- (2E)-1-(5-Hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-8-yl)-3-(4-hydroxyphenyl)-2-propen-1-one crotmadine

Description	Isodorsmanin A is an anti-inflammatory agent. Isodorsmanin A suppresses the production of inflammatory mediators and proinflammatory cytokines. Isodorsmanin A inhibits the phosphorylation of JNK, MAPK[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Inflammation/Immunology Signaling Pathways >> MAPK/ERK Pathway >> JNK
References	[1]. Chung YC, et al. Isodorsmanin A Prevents Inflammatory Response in LPS-Stimulated Macrophages by Inhibiting the JNK and NF-κB Signaling Pathways. Curr Issues Mol Biol. 2023 Feb 13;45(2):1601-1612.

Density	1.2±0.1 g/cm3
Boiling Point	549.9±50.0 °C at 760 mmHg
Melting Point	239-240℃
Molecular Formula	C₂₀H₂₀O₄
Molecular Weight	324.37
Flash Point	198.7±23.6 °C
Exact Mass	324.136169
PSA	66.76000
LogP	4.75
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.633

Hazard Codes	Xi