658-48-0
658-48-0 structure
- Name: a-methyl-D-tyrosine
- Chemical Name: (S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
- CAS Number: 658-48-0
- Molecular Formula: C10H13NO3
- Molecular Weight: 195.215
- Catalog: Biochemical Amino acids and their derivatives Tyrosine derivatives
- Create Date: 2018-06-16 11:44:35
- Modify Date: 2024-01-02 03:44:34
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α-Methyl-p-tyrosine is a competitive inhibitor of the enzyme tyrosine hydroxylase, which converts tyrosine to Levodopa (DOPA). α-Methyl-p-tyrosine is an orally active inhibitor of catecholamine synthesis which inhibits the hydroxylation of tyrosine to DOPA[1].
| Name | (S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid |
|---|---|
| Synonyms |
MFCD00004187
a-methyl-D-tyrosine a-methyl-dl-p-tyrosine EINECS 211-523-0 D-Tyrosine, α-methyl- (-)-α-Methyl-D-tyrosine D-tyrosine, a-methyl- α-Methyl-D-tyrosine |
| Description | α-Methyl-p-tyrosine is a competitive inhibitor of the enzyme tyrosine hydroxylase, which converts tyrosine to Levodopa (DOPA). α-Methyl-p-tyrosine is an orally active inhibitor of catecholamine synthesis which inhibits the hydroxylation of tyrosine to DOPA[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 383.7±32.0 °C at 760 mmHg |
| Melting Point | >300ºC(lit.) |
| Molecular Formula | C10H13NO3 |
| Molecular Weight | 195.215 |
| Flash Point | 185.9±25.1 °C |
| Exact Mass | 195.089539 |
| PSA | 83.55000 |
| LogP | 0.73 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.600 |
| Storage condition | −20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | YP2890000 |
| HS Code | 2922509090 |
| Precursor 8 | |
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| DownStream 3 | |
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |