15301-69-6

15301-69-6 structure

Name: BML-278
Chemical Name: flavoxate
CAS Number: 15301-69-6
Molecular Formula: C₂₄H₂₅NO₄
Molecular Weight: 391.460
Catalog: API Urinary system medication Diuretic
Create Date: 2018-02-04 08:00:00
Modify Date: 2024-01-02 11:57:17
Flavoxate is a potent and competitive phosphodiesterase (PDE) inhibitor. Flavoxate is an antispasmodic agent and muscarinic mAChR antagonist. Flavoxate shows moderate calcium antagonistic activity and local anesthetic effect. Flavoxate can be used for the research of overactive bladder (OAB) and lower urinary tract infections[1][2].

Name	flavoxate
Synonyms	flavoxate 3-Methylflavone-8-carboxylic Acid b-Piperidinoethyl Ester Genurin Flavossato [DCIT] Flavoxatum [INN-Latin] 3-Methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylic Acid 2-(1-Piperidinyl)ethyl Ester Flavoxato [INN-Spanish] MFCD00210291 Flavossato Flavoxate [INN:BAN] Flavoxatum REC 7-0040 2-(Piperidin-1-yl)ethyl-3-methyl-4-oxo-2-phenyl-4H-chromen-8-carboxylat 2-(Piperidin-1-yl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate 2-piperidin-1-ylethyl 3-methyl-4-oxo-2-phenylchromene-8-carboxylate 2-(1-Piperidinyl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate Urispas 2-piperidin-1-ylethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate 2-Piperidinoethyl 3-Methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylate EINECS 239-337-5 Bladderon Spasuret 2-Piperidinoethyl 3-Methylflavone-8-carboxylate Flavoxato 4H-1-Benzopyran-8-carboxylic acid, 3-methyl-4-oxo-2-phenyl-, 2-(1-piperidinyl)ethyl ester

Description	Flavoxate is a potent and competitive phosphodiesterase (PDE) inhibitor. Flavoxate is an antispasmodic agent and muscarinic mAChR antagonist. Flavoxate shows moderate calcium antagonistic activity and local anesthetic effect. Flavoxate can be used for the research of overactive bladder (OAB) and lower urinary tract infections[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
References	[1]. Arcaniolo D, et al. Flavoxate: present and future. Eur Rev Med Pharmacol Sci. 2015;19(5):719-31. [2]. Sugaya K, et al. Intravenous or local injections of flavoxate in the rostral pontine reticular formation inhibit urinary frequency induced by activation of medial frontal lobe neurons in rats. J Urol. 2014 Oct;192(4):1278-85.

91830-40-9

~96%

15301-69-6

Literature: Yamamoto Chemical Industrial Co., Ltd.; Osaka Municipal Government Patent: US4634768 A1, 1987 ;

91099-99-9

98-88-4

~92%

15301-69-6

Literature: Yamamoto Chemical Industrial Company, Limited; Osaka Municipal Government Patent: US4533732 A1, 1985 ;

91849-12-6

~80%

15301-69-6

Literature: Yamamoto Chemical Industrial Co., Ltd.; Osaka Municipal Government Patent: US4634768 A1, 1987 ;

Precursor 2
91099-99-9 98-88-4
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