264234-05-1

264234-05-1 structure

Name: 6',7'-Dihydroxybergamottin
Chemical Name: 6',7'-Dihydroxybergamottin
CAS Number: 264234-05-1
Molecular Formula: C₂₁H₂₄O₆
Molecular Weight: 372.412
Catalog: Natural product Coumarin
Create Date: 2017-03-16 15:41:23
Modify Date: 2024-01-04 16:38:24
(R)-6',7'-Dihydroxybergamottin ((R)-6′,7′-DHB) is a competitive inhibitor of human and rat CYP1A1 activity with Kis of 55 μM and 1.72 μM, respectively. (R)-6',7'-Dihydroxybergamottin has the potential for cancer research[1].

Name	6',7'-Dihydroxybergamottin
Synonyms	7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E,6R)-6,7-dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]- 4-{[(2E,6R)-6,7-Dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one

Description	(R)-6',7'-Dihydroxybergamottin ((R)-6′,7′-DHB) is a competitive inhibitor of human and rat CYP1A1 activity with Kis of 55 μM and 1.72 μM, respectively. (R)-6',7'-Dihydroxybergamottin has the potential for cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
References	[1]. Rebeca Santes-Palacios, et al. Inhibition of human and rat CYP1A1 enzyme by grapefruit juice compounds. Toxicol Lett. 2016 Sep 6:258:267-275.

Hazard Codes	Xi

Precursor 0
DownStream 1
486-60-2