DC Chemicals Limited
China
Product Name: LRRK2-IN-3
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2641054-60-4

2641054-60-4 structure

2641054-60-4 structure

Name: LRRK2-IN-3
Chemical Name: LRRK2-IN-3
CAS Number: 2641054-60-4
Molecular Formula: C₂₅H₂₉ClF₂N₆O₂
Molecular Weight: 518.99
Catalog: Signaling Pathways Autophagy LRRK2
Create Date: 2022-04-07 15:07:15
Modify Date: 2024-01-11 08:18:06
LRRK2-IN-3 (compoubd 24) is a potent, selective, orally active and brain-penetrant inhibitor LRRK2, with IC50 of 2.6 nM in human PBMCs. LRRK2-IN-3 can be used for the research of Parkinson's disease[1].

Name	LRRK2-IN-3

Description	LRRK2-IN-3 (compoubd 24) is a potent, selective, orally active and brain-penetrant inhibitor LRRK2, with IC50 of 2.6 nM in human PBMCs. LRRK2-IN-3 can be used for the research of Parkinson's disease[1].
Related Catalog	Signaling Pathways >> Autophagy >> LRRK2 Research Areas >> Neurological Disease
Target	IC50: 2.6 nM (hPBMCs LRRK2)[1]
References	[1]. Keylor MH, et, al. Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors. J Med Chem. 2022 Jan 13;65(1):838-856.

Molecular Formula	C₂₅H₂₉ClF₂N₆O₂
Molecular Weight	518.99