152743-19-6

152743-19-6 structure

Name: Nebadensin
Chemical Name: lysionotin
CAS Number: 152743-19-6
Molecular Formula: C₁₈H₁₆O₇
Molecular Weight: 344.315
Catalog: API Synthetic anti-infective drugs Anti-tuberculosis leprosy
Create Date: 2018-04-18 08:00:00
Modify Date: 2024-01-06 12:24:18
Lysionotin is a flavonoid isolated from few flower lysionotus herbs. Lysionotin efficiently inhibit α-Toxin (a pore-forming protein) expression and shows significant protection against S. aureus in vitro and in vivo. Lysionotin has the potential for the treatment of S. aureus induced pneumonia[1].

Name	lysionotin
Synonyms	shidiaolanjiasu Nebadensin 4H-1-Benzopyran-4-one, 5,7-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)- 5,7-Dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one 5,7-Dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

Description	Lysionotin is a flavonoid isolated from few flower lysionotus herbs. Lysionotin efficiently inhibit α-Toxin (a pore-forming protein) expression and shows significant protection against S. aureus in vitro and in vivo. Lysionotin has the potential for the treatment of S. aureus induced pneumonia[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	IC50: α-Toxin[1]
References	[1]. Teng Z, et al.Lysionotin attenuates Staphylococcus aureus pathogenicity by inhibiting α-toxin expression.Appl Microbiol Biotechnol. 2017 Sep;101(17):6697-6703.