2055896-77-8

2055896-77-8 structure

Name: MC-Val-Cit-PAB-Auristatin E
Chemical Name: MC-Val-Cit-PAB-Auristatin E
CAS Number: 2055896-77-8
Molecular Formula: C₆₈H₁₀₈N₁₁O₁₃
Molecular Weight: 1287.65
Catalog: Signaling Pathways Antibody-drug Conjugate Drug-Linker Conjugates for ADC
Create Date: 2019-09-09 18:37:51
Modify Date: 2024-01-01 23:39:40
MC-Val-Cit-PAB-Auristatin E has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-Auristatin E is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].

Name	MC-Val-Cit-PAB-Auristatin E

Description	MC-Val-Cit-PAB-Auristatin E has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-Auristatin E is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> Drug-Linker Conjugates for ADC
References	[1]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

Molecular Formula	C₆₈H₁₀₈N₁₁O₁₃
Molecular Weight	1287.65