- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Thrombin
- Price: ￥Inquiry/1mg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Thrombin
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
9002-04-4
9002-04-4 structure
- Name: Thrombin
- Chemical Name: Thrombin
- CAS Number: 9002-04-4
- Molecular Formula:
- Molecular Weight:
- Catalog: Biochemical Enzymes and coenzymes
- Create Date: 2019-02-28 12:16:41
- Modify Date: 2024-01-04 19:56:11
-
Thrombin is a trypsin-like allosteric serine protease that has a fundamental role in the clotting cascade.
| Name | Thrombin |
|---|---|
| Synonyms |
EINECS 232-648-7
MFCD00166053 |
| Description | Thrombin is a trypsin-like allosteric serine protease that has a fundamental role in the clotting cascade. |
|---|---|
| Related Catalog | |
| In Vitro | Thrombin is a serine protease known to have a fundamental role in the clotting cascade. In addition, Thrombin also mediates several cellular processes through a unique family of protease-activated receptors (PARS), where PAR-1 is the prototype. Thrombin and PAR-1 are highly expressed in the brain and regulate synaptic transmission and plasticity[1]. Thrombin belongs to the chymotrypsin family and is generated by proteolytic cleavage of its inactive precursor prothrombin by the proThrombinase complex. Thrombin mediates the conversion of fibrinogen to fibrin, the main constituent of a blood clot. Furthermore, Thrombin activates the blood coagulation factors V, VIII, XI, XIII and the anticoagulant protein C[2]. |
| References |
| Appearance | powder | white |
|---|---|
| Storage condition | −20°C |
| Water Solubility | H2O: 1 mL/vial clear to slightly hazy, colorless solution |
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H315-H319-H334-H335 |
| Precautionary Statements | P261-P305 + P351 + P338-P342 + P311 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xn,B,Xi |
| Risk Phrases | 36/37/38-42 |
| Safety Phrases | 22-24/25-36/37-26-24 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | XO8950000 |