Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: EXENDIN-3
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Taiwan Oyi peptide Co. Ltd
China
Product Name: Exendin-3 trifluoroacetate salt
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Vinnie

130357-25-4

130357-25-4 structure

130357-25-4 structure

Name: Exendin-3 trifluoroacetate salt
Chemical Name: EXENDIN-3
CAS Number: 130357-25-4
Molecular Formula: C₁₈₄H₂₈₂N₅₀O₆₁S
Molecular Weight: 4202.57
Catalog: Biochemical Peptide
Create Date: 2018-12-04 22:59:21
Modify Date: 2024-01-02 12:52:42
Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn .

Name	EXENDIN-3
Synonyms	MFCD00240170

Description	Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn .
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Peptides
Target	VIP receptor, putative exendin receptor[1]
In Vitro	Exendin-3 interacts with at least two receptors on guinea pig pancreatic acini; at high concentrations (>100 nM) the peptide interacts with VIP receptors, thereby causing a large increase in cAMP and stimulating amylase release; at lower concentrations (0.1-3 nM) the peptide interacts with a putative exendin receptor, thereby causing a smaller increase in cAMP of undetermined function[1].
Kinase Assay	Effect of increasing concentrations of two VIP receptor antagonists on the increase in amylase release are observed with VIP, secretin, or exendin-3. Male Hartley guinea pigs Acini were incubated with VIP (1 nM), secretin (1 μM), or Exendin-3 (1 μM) for 30 min at 37°C, alone or in combination with indicated concentrations of [AcTyr, D-Phe]GRF 1-29 amide (solid symbols) or [4-Cl-D-Phe,Leu] VIP (open symbols)[1].
References	[1]. Raufman JP, et al. Exendin-3, a novel peptide from Heloderma horridum venom, interacts with vasoactive intestinal peptide receptors and a newly described receptor on dispersed acini from guinea pig pancreas. Description of exendin-3(9-39) amide, a specific exendin receptor antagonist. J Biol Chem. 1991 Feb 15;266(5):2897-902.

Molecular Formula	C₁₈₄H₂₈₂N₅₀O₆₁S
Molecular Weight	4202.57
Storage condition	−20°C

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