180288-69-1

180288-69-1 structure

Name: Trastuzumab
Chemical Name: Trastuzumab
CAS Number: 180288-69-1
Molecular Formula: C₆₄₇₀H₁₀₀₁₂N₁₇₂₆O₂₀₁₃S₄₂
Molecular Weight: 145531.50
Catalog: API Antineoplastic agents Natural source antineoplastic agents
Create Date: 2018-02-08 08:00:00
Modify Date: 2024-01-02 20:04:40
Trastuzumab (PBS) is a humanized IgG1 monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab (PBS) has the potential for HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer research.

Name	Trastuzumab
Synonyms	Herceptin

Description	Trastuzumab (PBS) is a humanized IgG1 monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab (PBS) has the potential for HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer research.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
References	[1]. Sliwkowski MX, et al. Nonclinical studies addressing the mechanism of action of trastuzumab. Semin Oncol. 1999 Aug;26(4 Suppl 12):60-70. [2]. Hudis CA, et al. Trastuzumab--mechanism of action and use in clinical practice. N Engl J Med. 2007 Jul 5;357(1):39-51. [3]. Barok M, et al. Trastuzumab causes antibody-dependent cellular cytotoxicity-mediated growth inhibition of submacroscopic JIMT-1 breast cancer xenografts despite intrinsic drug resistance. Mol Cancer Ther. 2007 Jul;6(7):2065-72.

Molecular Formula	C₆₄₇₀H₁₀₀₁₂N₁₇₂₆O₂₀₁₃S₄₂
Molecular Weight	145531.50