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112-59-4

112-59-4 structure
112-59-4 structure

Name Diethylene Glycol Monohexyl Ether
Synonyms Ethanol, 2-[2-(hexyloxy)ethoxy]-
2-(2-Hexyloxyethoxy)ethanol,C6E2,Hexyldiglycol
EINECS 203-988-3
Diethylene glycol monohexyl ether
MFCD00010703
2-[2-(Hexyloxy)ethoxy]ethanol
Ethanol, 2-[2- (hexyloxy)ethoxy]-
2-(2-hexoxyethoxy)ethanol
Hexyl Carbitol
2-(2-Hexyloxyethoxy)ethanol
Density 0.933
Boiling Point 260.0±0.0 °C at 760 mmHg
Melting Point −40 °C(lit.)
Molecular Formula C10H22O3
Molecular Weight 190.280
Flash Point 140.0±0.0 °C
Exact Mass 190.156891
PSA 38.69000
LogP 1.50
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.437

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KL2625000
CHEMICAL NAME :
Ethanol, 2-((2-hexyloxy)ethoxy)-
CAS REGISTRY NUMBER :
112-59-4
BEILSTEIN REFERENCE NO. :
1743959
LAST UPDATED :
199712
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C10-H22-O3
MOLECULAR WEIGHT :
190.32
WISWESSER LINE NOTATION :
Q2O2O6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 82,377,1944
TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/3/1971
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/3/1971
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,640,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538682
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3160 uL/kg
TOXIC EFFECTS :
Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea Blood - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538680
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1500 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4280 No. of Facilities: 85 (estimated) No. of Industries: 4 No. of Occupations: 10 No. of Employees: 808 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4280 No. of Facilities: 6 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 18 (estimated)
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H312-H318
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn: Harmful;
Risk Phrases R21
Safety Phrases S26-S36/37-S46
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS KL2625000

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112-59-4 structure

112-59-4

Literature: Journal of the Chemical Society, , p. 2065

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112-59-4 structure

112-59-4

Literature: Roczniki Chemii, , vol. 47, p. 2045 - 2054

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112-59-4 structure

112-59-4

Literature: Journal of Pharmaceutical Sciences, , vol. 64, # 4 p. 693 - 695

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112-59-4 structure

112-59-4

Literature: Bulletin des Societes Chimiques Belges, , vol. 65, p. 453,470