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  • Product Name: Altrenogest
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Hot CAS#:
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850-52-2

850-52-2 structure
850-52-2 structure
  • Name: Altrenogest
  • Chemical Name: Altrenogest
  • CAS Number: 850-52-2
  • Molecular Formula: C21H26O2
  • Molecular Weight: 310.430
  • Catalog: Biochemical Inhibitor Endocrinology & Hormones Estrogen/progestogen Receptor agonist
  • Create Date: 2018-05-20 08:00:00
  • Modify Date: 2024-01-02 14:55:24
  • Altrenogest(A35957; RU2267) is a progestogen structurally related to veterinary steroid trenbolone.Target: Progesterone ReceptorAltrenogest is a progestogen structurally related to veterinary steroid trenbolone. Treatment of embryo-recipient mares with altrenogest appears to be beneficial in extending the degree of donor-recipient synchrony required for successful embryo transfer. Altrenogest treatment also seems to be conductive to pregnancy maintenance in recipients experiencing luteal dysfunction [1]. The oil and gel altrenogest preparations are equally effective in modulating estrous behavior and time to estrus and ovulation. Altrenogest treatment started late in diestrus appears to result in a high incidence of ovulation during treatment and when luteolysis and ovulation occur during treatment; the subsequent luteal phase is frequently prolonged due to failure of regression of the CL [2].
Name Altrenogest
Synonyms (17b)-17-Hydroxy-17-(2-propenyl)estra-4,9,11-trien-3-one
13b-Methyl-17a-allyl-D4,9,11-gonatriene-17b-ol-3-one
(17β)-17-Hydroxy-17-(2-propenyl)estra-4,9,11-trien-3-one
Estra-4,9,11-trien-3-one, 17-hydroxy-17-(2-propen-1-yl)-, (17β)-
Allyltrenbolone
r2267
17α-Allyl-17-hydroxyestra-4,9,11-trien-3-one
altregonest
(17β)-17-hydroxy-17-(prop-2-en-1-yl)estra-4,9,11-trien-3-one
Altrenogest
REGU-MATE
17-allyltrenbolone
ru2267
Estra-4,9,11-trien-3-one, 17-α-allyl-17-hydroxy-
(8S,13S,14S,17R)-17-Allyl-17-hydroxy-13-methyl-1,2,6,7,8,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
drc6246
Estra-4,9,11-trien-3-one, 17β-hydroxy-17-(2-propenyl)-
Regumate
17a-Allyl-17-hydroxyestra-4,9,11-trien-3-one
Description Altrenogest(A35957; RU2267) is a progestogen structurally related to veterinary steroid trenbolone.Target: Progesterone ReceptorAltrenogest is a progestogen structurally related to veterinary steroid trenbolone. Treatment of embryo-recipient mares with altrenogest appears to be beneficial in extending the degree of donor-recipient synchrony required for successful embryo transfer. Altrenogest treatment also seems to be conductive to pregnancy maintenance in recipients experiencing luteal dysfunction [1]. The oil and gel altrenogest preparations are equally effective in modulating estrous behavior and time to estrus and ovulation. Altrenogest treatment started late in diestrus appears to result in a high incidence of ovulation during treatment and when luteolysis and ovulation occur during treatment; the subsequent luteal phase is frequently prolonged due to failure of regression of the CL [2].
Related Catalog
References

[1]. Parry-Weeks, L.C. and D.W. Holtan, Effect of altrenogest on pregnancy maintenance in unsynchronized equine embryo recipients. J Reprod Fertil Suppl, 1987. 35: p. 433-8.

[2]. Daels, P.F., et al., Persistence of the luteal phase following ovulation during altrenogest treatment in mares. Theriogenology, 1996. 46(5): p. 799-811.
Density 1.1±0.1 g/cm3
Boiling Point 495.6±45.0 °C at 760 mmHg
Melting Point 120ºC
Molecular Formula C21H26O2
Molecular Weight 310.430
Flash Point 210.1±21.3 °C
Exact Mass 310.193268
PSA 37.30000
LogP 3.49
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.594

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KG7745000
CHEMICAL NAME :
Estra-4,9,11-trien-3-one, 17-alpha-allyl-17-hydroxy-
CAS REGISTRY NUMBER :
850-52-2
LAST UPDATED :
199509
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C21-H26-O2
MOLECULAR WEIGHT :
310.47
WISWESSER LINE NOTATION :
L E5 B666 OV AU CU MUTJ E1 FQ F2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3 mg/kg
SEX/DURATION :
female 18 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
THGNBO Theriogenology. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1974- Volume(issue)/page/year: 16,195,1981
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2500 ug/kg
SEX/DURATION :
female 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
JANSAG Journal of Animal Science. (American Soc. of Animal Science, 309 W. Clark St., Champaign, IL 61820) V.1- 1942- Volume(issue)/page/year: 70,1357,1992
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
810 ug/kg
SEX/DURATION :
female 15 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Maternal Effects - other effects
REFERENCE :
JRFSAR Journal of Reproduction and Fertility, Supplement. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) No.1- 1966- Volume(issue)/page/year: 32,193,1982
WGK Germany 3.0
RTECS KG7745000
HS Code 2937290090
HS Code 2937290090

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title: CAS No. 850-52-2 | Chemsrc address: https://www.chemsrc.com/en/baike/1193331.html

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