- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: tert-Butyl (6-bromohexyl)carbamate
- Price: ￥Inquiry/1mg
- Purity: 97.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: N-Boc-6-Bromohexylamin
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
142356-33-0
142356-33-0 structure
- Name: tert-Butyl (6-bromohexyl)carbamate
- Chemical Name: tert-Butyl (6-bromohexyl)carbamate
- CAS Number: 142356-33-0
- Molecular Formula: C11H22BrNO2
- Molecular Weight: 280.202
- Catalog: Chemical reagent Organic reagent Imide
- Create Date: 2018-06-22 17:27:42
- Modify Date: 2024-01-10 11:12:54
-
Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1].
| Name | tert-Butyl (6-bromohexyl)carbamate |
|---|---|
| Synonyms |
tert-butyl N-(6-bromohexyl)carbamate
2-Methyl-2-propanyl (6-bromohexyl)carbamate tert-Butyl (6-bromohexyl)carbamate Carbamic acid, N-(6-bromohexyl)-, 1,1-dimethylethyl ester |
| Description | Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Jan Anderl, et al. Amatoxin-antibody conjugates. WO2016142049A1. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 340.1±25.0 °C at 760 mmHg |
| Molecular Formula | C11H22BrNO2 |
| Molecular Weight | 280.202 |
| Flash Point | 159.5±23.2 °C |
| Exact Mass | 279.083374 |
| PSA | 38.33000 |
| LogP | 3.63 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.473 |
| Storage condition | 2-8°C |
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Phrases | R41 |
| Safety Phrases | 26-39 |
| RIDADR | UN 3082 9/PG 3 |
| WGK Germany | 3 |
| HS Code | 2924199090 |
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| Literature: Keller; Haner Helvetica Chimica Acta, 1993 , vol. 76, # 2 p. 884 - 892 |
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| Literature: US6878715 B1, ; |
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| Literature: US2002/28823 A1, ; |
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| Literature: Journal of Medicinal Chemistry, , vol. 37, # 16 p. 2537 - 2551 |
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 15 p. 4208 - 4212 |
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| Literature: Journal of the Chemical Society, Perkin Transactions 2, , # 5 p. 923 - 927 |
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| Literature: Journal of the Chemical Society, Perkin Transactions 2, , # 5 p. 923 - 927 |
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| Literature: Journal of the Chemical Society, Perkin Transactions 2, , # 5 p. 923 - 927 |
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 15 p. 4208 - 4212 |
| Precursor 9 | |
|---|---|
| DownStream 1 | |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |