546-88-3

546-88-3 structure

Name: Acetohydroxamic acid
Chemical Name: acetohydroxamic acid
CAS Number: 546-88-3
Molecular Formula: C₂H₅NO₂
Molecular Weight: 75.067
Catalog: API Urinary system medication Other urinary system medication
Create Date: 2018-05-20 08:00:00
Modify Date: 2024-01-02 20:22:33
Acetohydroxamic acid is a potent and irreversible inhibitor of bacterial and plant urease and also used as adjunctive therapy in chronic urinary infection.Target: UreaseAcetohydroxamic acid selectively inhibits arachidonate 5-lipoxygenase and thus has potential use in the treatment of asthma.

Name	acetohydroxamic acid
Synonyms	Acetamide, N-hydroxy- Acetohydroxamic acid methanecarbohydroxamic acid EINECS 208-913-8 N-Hydroxyacetamide N-acetylhydroxylamine Acetomenadione acethydroxamic acid methylenehydroxamic acid Acetylhydroxylamine AHA Lithostat Acethydroxamsaure MFCD00009994 Acetohydroxamic Acetic acid,oxime Acetic Acid Oxime

Description	Acetohydroxamic acid is a potent and irreversible inhibitor of bacterial and plant urease and also used as adjunctive therapy in chronic urinary infection.Target: UreaseAcetohydroxamic acid selectively inhibits arachidonate 5-lipoxygenase and thus has potential use in the treatment of asthma.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
References	[1]. Sharma M, et al. Biotransformation of Acetamide to Acetohydroxamic Acid at Bench Scale Using Acyl Transferase Activity of Amidase of Geobacillus pallidus BTP-5x MTCC 9225. Indian J Microbiol. 2012 Mar;52(1):76-82.

Density	1.2±0.1 g/cm3
Boiling Point	231.4ºC at 760 mmHg
Melting Point	88-90 °C(lit.)
Molecular Formula	C₂H₅NO₂
Molecular Weight	75.067
Exact Mass	75.032028
PSA	49.33000
LogP	-1.59
Index of Refraction	1.421
Stability	Moisture and Temperature Sensitive

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 152,225,1985

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H360
Precautionary Statements	P201-P308 + P313
Personal Protective Equipment	Eyeshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R61
Safety Phrases	S53-S45
RIDADR	3263
WGK Germany	3
RTECS	AK8157000
Packaging Group	II
HS Code	2942000000

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%