L-缬氨酸-D1

更新时间:2024-01-21 16:51:31

L-缬氨酸-D1结构式
L-缬氨酸-D1结构式
委托求购
常用名 L-缬氨酸-D1 英文名 l-valine-2-d1
CAS号 77257-03-5 分子量 118.15300
密度 N/A 沸点 N/A
分子式 C5H10DNO2 熔点 N/A
MSDS N/A 闪点 N/A

 L-缬氨酸-D1用途


L-缬氨酸-d1是氘标记的L-缬氨酸。L-缬氨酸是20种蛋白源性氨基酸之一。L-缬氨酸是一种必需氨基酸[1]。

 L-缬氨酸-D1名称

中文名 L-缬氨酸-D1
英文名 l-valine-2-d1
英文别名 更多

 L-缬氨酸-D1生物活性

描述 L-缬氨酸-d1是氘标记的L-缬氨酸。L-缬氨酸是20种蛋白源性氨基酸之一。L-缬氨酸是一种必需氨基酸[1]。
相关类别
体外研究 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注[1]。
参考文献

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[3]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[4]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[5]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[6]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[7]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[8]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

[9]. Oldiges, et al. Application of metabolic engineering for the biotechnological production of L-valine. Appl Microbiol Biotechnol 98, 5859–5870 (2014).

 L-缬氨酸-D1物理化学性质

分子式 C5H10DNO2
分子量 118.15300
精确质量 118.08500
PSA 63.32000
LogP 0.75460

 L-缬氨酸-D1合成线路

~57%

L-缬氨酸-D1结构式

L-缬氨酸-D1

77257-03-5

文献:Faleev, N. G.; Ruvinov, S. B.; Saporovskaya, M. B.; Belikov, V. M.; Zakomyrdina, L. N.; et al. Tetrahedron Letters, 1990 , vol. 31, # 48 p. 7051 - 7054

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L-缬氨酸-D1结构式

L-缬氨酸-D1

77257-03-5

文献:Tachibana, Yoji; Ando, Makoto; Kuzuhara, Hiroyoshi Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 12 p. 3652 - 3656

~%

L-缬氨酸-D1结构式

L-缬氨酸-D1

77257-03-5

文献:Oh, Joong-Suk; Kim, Kyung Il; Song, Choong Eui Organic and Biomolecular Chemistry, 2011 , vol. 9, # 23 p. 7983 - 7985

~%

L-缬氨酸-D1结构式

L-缬氨酸-D1

77257-03-5

文献:Baldwin; Adlington; Ting; et al. Tetrahedron, 1985 , vol. 41, # 16 p. 3339 - 3343

~%

L-缬氨酸-D1结构式

L-缬氨酸-D1

77257-03-5

文献:Faleev, N. G.; Ruvinov, S. B.; Saporovskaya, M. B.; Belikov, V. M.; Zakomyrdina, L. N.; et al. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1989 , vol. 38, # 10 p. 2154 - 2156 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1989 , # 10 p. 2341 - 2343

 L-缬氨酸-D1上下游产品

L-缬氨酸-D1上游产品  3

L-缬氨酸-D1下游产品  0

 L-缬氨酸-D1英文别名

L-[2',3',5',6'-2H4]tyrosine
L-tyrosine-d4
[2,3,5,6-2H]-L-tyrosine
L-Tyrosine-d4 (phenyl-d4)
L-4-Hydroxyphenyl-2,3,5,6-d4-alanine
<2',3',5',6'-2H4>-L-tyrosine
[2H4]-L-Tyrosine
L-[(2)H4]tyrosine
L-Tyrosine-(phenyl-d4)
L-[2-2H]valine