TGFβRI-IN-5

Modify Date: 2025-09-25 18:56:04

TGFβRI-IN-5 Structure
TGFβRI-IN-5 structure
Common Name TGFβRI-IN-5
CAS Number 2541690-15-5 Molecular Weight 328.28
Density N/A Boiling Point N/A
Molecular Formula C16H12N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TGFβRI-IN-5


TGFβRI-IN-5 (Compound 4b) is a potent inhibitor of TGFβRI with an IC50 of 0.08 μM. TGFβRI-IN-5 displays amazing anticancer activity 5–7 times that of reference drug against all the tested cell lines. TGFβRI-IN-5 enhances apoptosis and arrested G2/M phase of cell cycle[1].

 Names

Name TGFβRI-IN-5

 TGFβRI-IN-5 Biological Activity

Description TGFβRI-IN-5 (Compound 4b) is a potent inhibitor of TGFβRI with an IC50 of 0.08 μM. TGFβRI-IN-5 displays amazing anticancer activity 5–7 times that of reference drug against all the tested cell lines. TGFβRI-IN-5 enhances apoptosis and arrested G2/M phase of cell cycle[1].
Related Catalog
References

[1]. Ismail MMF, et al. Design and synthesis of novel tranilast analogs: Docking, antiproliferative evaluation and in-silico screening of TGFβR1 inhibitors. Bioorg Chem. 2020;105:104368.

 Chemical & Physical Properties

Molecular Formula C16H12N2O6
Molecular Weight 328.28
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