Methyl-PEG12-Azide

Modify Date: 2024-01-13 23:27:43

Methyl-PEG12-Azide Structure
Methyl-PEG12-Azide structure
Common Name Methyl-PEG12-Azide
CAS Number 2170098-29-8 Molecular Weight 585.69
Density N/A Boiling Point N/A
Molecular Formula C25H51N3O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methyl-PEG12-Azide


m-PEG12-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG12-azide

 Methyl-PEG12-Azide Biological Activity

Description m-PEG12-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H51N3O12
Molecular Weight 585.69
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