Taltobulin intermediate-10

Modify Date: 2025-10-14 20:43:41

Taltobulin intermediate-10 Structure
Taltobulin intermediate-10 structure
Common Name Taltobulin intermediate-10
CAS Number 1822592-72-2 Molecular Weight 321.41
Density N/A Boiling Point N/A
Molecular Formula C18H27NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Taltobulin intermediate-10


Taltobulin intermediate-10 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].

 Names

Name Taltobulin intermediate-10

 Taltobulin intermediate-10 Biological Activity

Description Taltobulin intermediate-10 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].
Related Catalog
References

[1]. Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45.  

 Chemical & Physical Properties

Molecular Formula C18H27NO4
Molecular Weight 321.41
InChIKey FTEKZDUWMPFROI-UHFFFAOYSA-N
SMILES COC(=O)C(N(C)C(=O)OC(C)(C)C)C(C)(C)c1ccccc1
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.