Filgotinib maleate structure
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Common Name | Filgotinib maleate | ||
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CAS Number | 1802998-75-9 | Molecular Weight | 541.58 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C25H27N5O7S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Filgotinib maleateFilgotinib (maleate) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM and 116 nM for JAK1, JAK2, JAK3 and TYK2, respectively. Filgotinib (maleate) can be used for rheumatoid arthritis (RA) and Crohn's disease research[1][2]. |
Name | Filgotinib maleate |
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Description | Filgotinib (maleate) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM and 116 nM for JAK1, JAK2, JAK3 and TYK2, respectively. Filgotinib (maleate) can be used for rheumatoid arthritis (RA) and Crohn's disease research[1][2]. |
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Related Catalog | |
Target |
JAK1:10 nM (IC50) JAK2:28 nM (IC50) JAK3:810 nM (IC50) Tyk2:116 nM (IC50) |
In Vitro | Filgotinib (maleate) (1-10 μM) inhibits Th1 and Th2 differentiation in a dose-dependent manner[1]. |
References |
Molecular Formula | C25H27N5O7S |
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Molecular Weight | 541.58 |