Elobixibat hydrate

Modify Date: 2024-01-04 20:29:33

Elobixibat hydrate Structure
Elobixibat hydrate structure
Common Name Elobixibat hydrate
CAS Number 1633824-78-8 Molecular Weight 713.90
Density N/A Boiling Point N/A
Molecular Formula C36H47N3O8S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Elobixibat hydrate


Elobixibat hydrate is a potent ileal bile acid transporter (IBAT) inhibitor, with IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. Elobixibat hydrate can be used for chronic idiopathic constipation (CIC) research[1].

 Names

Name Elobixibat hydrate

 Elobixibat hydrate Biological Activity

Description Elobixibat hydrate is a potent ileal bile acid transporter (IBAT) inhibitor, with IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. Elobixibat hydrate can be used for chronic idiopathic constipation (CIC) research[1].
Related Catalog
Target

IC50: 0.53±0.17 nM (human IBAT), 0.13±0.03 nM (mouse IBAT), 5.8±1.6 nM (canine IBAT)[1].

References

[1]. Wong BS, et al. Elobixibat for the treatment of constipation. Expert Opin Investig Drugs. 2013 Feb; 22(2):277-84.

 Chemical & Physical Properties

Molecular Formula C36H47N3O8S2
Molecular Weight 713.90