4β-Hydroxycholesterol-d4

Modify Date: 2024-01-05 18:52:00

4β-Hydroxycholesterol-d4 structure	Common Name	4β-Hydroxycholesterol-d4
	CAS Number	1363529-44-5	Molecular Weight	406.67800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₄₂D₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 4β-Hydroxycholesterol-d4

4β-Hydroxycholesterol-d4 is the deuterium labeled 4β-Hydroxycholesterol. 4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation[1][2].

Name	4β-Hydroxy Cholesterol-d4
Synonym	More Synonyms

Description	4β-Hydroxycholesterol-d4 is the deuterium labeled 4β-Hydroxycholesterol. 4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation[1][2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Granchi C, Rizzolio F, Bordoni V, Caligiuri I, Manera C, Macchia M, Minutolo F, Martinelli A, Giordano A, Tuccinardi T. 4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors. J Enzyme Inhib Med Chem. 2016;31(1):137

Molecular Formula	C₂₇H₄₂D₄O₂
Molecular Weight	406.67800
Exact Mass	406.37500
PSA	40.46000
LogP	6.35950

4Beta-Hydroxy Cholesterol-d4 (Major)

4β-Hydroxycholesterol-d4

Use of 4β-Hydroxycholesterol-d4

Names

4β-Hydroxycholesterol-d4 Biological Activity

Chemical & Physical Properties

Synonyms