SAR127303

Modify Date: 2024-04-06 16:45:21

SAR127303 Structure
SAR127303 structure
Common Name SAR127303
CAS Number 1352011-38-1 Molecular Weight 482.83
Density N/A Boiling Point N/A
Molecular Formula C16H17ClF6N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SAR127303


SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL.

 Names

Name SAR127303

 SAR127303 Biological Activity

Description SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL.
References 1. Wang L, Mori W, Cheng R, Yui J, Hatori A, Ma L, Zhang Y, Rotstein BH, Fujinaga M, Shimoda Y, Yamasaki T, Xie L, Nagai Y, Minamimoto T, Higuchi M, Vasdev N, Zhang MR, Liang SH. Synthesis and Preclinical Evaluation of Sulfonamido-based [(11)C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase. Theranostics. 2016 May 21;6(8):1145-59. doi: 10.7150/thno.15257. eCollection 2016. PubMed PMID: 27279908; PubMed Central PMCID: PMC4893642.

 Chemical & Physical Properties

Molecular Formula C16H17ClF6N2O4S
Molecular Weight 482.83
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